EMPOWER: Randomized Trial of Online Chronic Pain Management Program to Reduce Reliance on Opioid Analgesic Medications

This study will determine whether an innovative, accessible E-health intervention can assist with reduced opioid reliance in chronic pain patients, which can, ultimately, reduce risks of unintended opioid overdose and death. Importantly, the study will contribute to a better understanding of the mechanisms contributing to opioid use reduction while managing pain. The findings may assist in developing treatment options for a population at risk for opioid adverse effects.

Potential participants will be identified through electronic health record (EHR) queries at participating sites. Participants will be assessed at baseline, at the end of the 4-month treatment period, and at 6 months following end-of-treatment through an electronic data capture system accessed by the participants. Other outcome data will be obtained from the participant's EHR data.

Inclusion criteria

• Be 25-80 years of age
• Be able to understand the study, and having understood, provide informed consent in English
• Have a daily average prescribed MED ≥ 20 mg over a recent three-month period
• Have a chronic pain-related diagnosis
• Self-report current use of opioid medication(s) to treat pain
• Have a Brief Pain Inventory Pain Intensity score ≥3
• Have internet access and a working email account

Exclusion criteria

• Be anyone who, in the judgment of study staff, would be unlikely to complete the study (e.g., planning to change to a different primary care clinic, have a terminal illness, etc.)
• Be unwilling/unable to complete the WebNeuro assessments
• Be pregnant
• Be a prisoner