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OpenTrials
Completed

NCT Number: NCT03303443

Empirical Mode Decomposition in the Electroencephalogram

Bispectral index (BIS), a standard monitor for perioperative monitor of patient's conscious level, is a noninvasive medical technique for monitoring and recording the electrical activity of brain.

Completed

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Key information

Conditions

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Feng-Fang Tsai

Taipei, 100, Taiwan

About this study

The electroencephalogram and BIS data have lots of information. Fourier transformation to decompose EEG was first applied on the EEG signaling until now. The disadvantages of Fourier transformation is hard to deal with physical signals, which was modulated by autonomic system and factors. The Hilbert-Huang transform (HHT) was proposed to decompose EEG signal into intrinsic mode functions (IMF) since 2004. HHT can obtain instantaneous frequency data and work well for data that is nonstationary and nonlinear. HHT have been applied for wild ranges, not only in the analysis of arrhythmia for medical and public health fields, but also in the earthquake detection and earth physics detection…etc.

The relationship between frontal EEG patterns and general anesthesia remain poorly understood. It can only say that the increase in frontal EEG power and shift power to lower frequencies during general anesthesia from publications. The investigators are going to compare the EEG signal between generations, try to find the difference in aging using empirical mode decomposition method.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 20-40y/o or over 60y/o
  • Scheduled for low risk general anesthesia
  • Suitable for surgery after interviewed by anesthesiologist

Exclusion criteria

  • Not suitable for general anesthesia
  • High risk patient
  • Allergic to the EEG sensor

Treatment and study plan

Primary outcomes

  1. EEG power calculation

    Time frame: During the operation time.

    The investigator use root mean square energy to calculate EEG power.

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

Empirical Mode Decomposition in the Electroencephalogram During General Anesthesia Between Generations

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Oct 6, 2017
Registry last updated
Jun 5, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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