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NCT Number: NCT07532499

EMG-Triggered Electrical Stimulation After Median/Ulnar Nerve Repairs

Immobilization following median and/or ulnar nerve repairs results in strength loss in the wrist and finger extensor muscles. Given the critical importance of wrist extension for functional grip, this condition significantly restricts hand functions. Therefore, this study aims to investigate the effects of EMG-triggered electrical stimulation applied to the wrist and finger extensors, in addition to conventional physiotherapy, on functional outcomes in patients undergoing median and/or ulnar nerve repair, with the objective of restoring extensor muscle weakness induced by immobilization.

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Key information

Conditions

Peripheral Nerve Injuries Median Nerve Injury Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Trauma, Nervous System Ulnar Nerve Injury Wounds and Injuries

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Intact communication skills
  • No prior history of neurological, orthopedic, rheumatologic, or metabolic diseases affecting the involved extremity

Exclusion criteria

  • Presence of concomitant central nervous system involvement
  • Pregnancy
  • Patients with cardiac pacemakers
  • Patients with cardiac arrhythmias
  • Patients with epilepsy

Treatment and study plan

EMG-triggered electrical stimulation

Other

This group will receive EMG-triggered electrical stimulation therapy in addition to conventional physiotherapy in the 5th week.The EMG-triggered electrical stimulation protocol will be conducted over 12 sessions (3 days/week for 4 weeks). Surface electrodes will be placed parallel to the fibers of the wrist and finger extensors-specifically the EDC, ECRL/B, and ECU-using anatomical landmarks and palpation. Following a baseline calibration (5s contraction/10s rest) to establish a microvolt threshold, the device will require active cognitive participation from the patient to initiate stimulation. Once the threshold is exceeded, stimulation will be delivered at 60 Hz with a 300 µS pulse width and 0.5s ramp times. The procedure involves 10 repetitions per muscle, utilizing a 10s contraction and 30s rest cycle to enhance functional recovery.

conventional physiotherapy group

Other

The conventional physiotherapy program will comprise splinting, edema control, range of motion exercises, and resistance training.

Primary outcomes

  1. Manual muscle test

    Time frame: At 12 and 24 weeks after surgery.

Secondary outcomes

  1. Gross and fine grip strength measurements by hand dynamometry and pinch gauge (kg)

    Time frame: At 12 and 24 weeks after surgery.

  2. Assessment of hand function via Michigan Hand Outcomes Questionnaire

    Time frame: At 12 and 24 weeks after surgery

    The score for each domain and the total score range from min 0 to max 100. For all domains except pain, a higher score denotes better hand performance or satisfaction. For the pain domain, a higher score indicates more pain.

Study contacts

Contact information is provided by the study sponsor or research team.

Umut Eraslan

CONTACT

[email protected]

+905444126520

Sponsors and collaborators

Lead sponsor

Pamukkale University

Other

Registry information

Official study title

The Impact of EMG-Triggered Electrical Stimulation of Extensor Muscles on Functional Status Following Median and/or Ulnar Nerve Repairs: A Single-Blind, Randomized Controlled Study

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 16, 2026
Registry last updated
Apr 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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