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NCT Number: NCT06230718

EMG Analysis in ABI: Motor Imagery and Action

This study focuses on electromyographic analysis of upper limb muscle activation in stroke survivors during Motor Imagery (MI) and Action Observation (AO) rehabilitation techniques. By measuring muscle activity in the wrist and finger flexors and extensors, the research seeks to understand the impact of MI and AO on motor function recovery post-stroke. Conducted at the University of Salamanca, the study involves stroke survivors participating in a series of three experimental sessions. The analysis will correlate electromyographic responses with functional independence, limb functionality, and cognitive factors. The research aims to contribute to the fields of occupational therapy and physiotherapy, offering insights into effective rehabilitation methods for improving quality of life in stroke survivors.

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Key information

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universidad de Salmanca

Salamanca, 37007, Spain

Location status: Recruiting

Location contact

Ana María Martín Nogueras

CONTACT

[email protected]

677510296

Ana María Martín Nogueras, Dr

PRINCIPAL_INVESTIGATOR

AnaBelen Calvo Vera, Dr

PRINCIPAL_INVESTIGATOR

Beatriz María Bermejo Gil, Dr

PRINCIPAL_INVESTIGATOR

Beatriz María Bermejo Gil, Dr.

CONTACT

[email protected]

622289468

Sara Santiago Marín, Phd Student

PRINCIPAL_INVESTIGATOR

About this study

This study investigates muscle activation in the upper limbs of stroke survivors using electromyographic analysis during Motor Imagery (MI) and Action Observation (AO). Stroke, a major cause of disability, often results in motor impairments in the upper limb, impacting daily activities. The research focuses on innovative rehabilitation techniques based on neuroplasticity, such as MI and AO, stimulated by the discovery of mirror neurons.

The primary goal is to record upper limb muscle activation during MI and AO, using surface electromyography to measure activation in wrist and finger flexors and extensors. The study will also explore the relationship between electromyographic responses and factors like daily activity independence, limb functionality, quality of life, mental evocation ability, and cognitive impairment.

Conducted at the University of Salamanca, the study will recruit stroke survivors for a three-session experimental protocol involving control, MI, and AO conditions. Data will be analyzed with SPSS Statistics, ensuring anonymity and ethical compliance. The research aims to enhance understanding of effective neurorehabilitation techniques, contributing to the fields of occupational therapy and physiotherapy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being over 18 years of age
  • Diagnoses of established stroke
  • Present limitations or motor response deficiencies in the upper limb
  • Maintain cognitive functions with the ability to follow the instructions of the interventions and evaluations (MOCA>14)

Exclusion criteria

  • Diagnosed with mental illness before the stroke
  • Other systemic conditions on the central nervous system
  • Cardiorespiratory system pathologies in severe cases
  • Acute period, fever, muscle inflammation or myopathies
  • Any type of vascular and organic insufficiency
  • Liver disease or skin lesions in the area of application of the electrodes.

Treatment and study plan

Motor Imagery (MI)

Other

mental process where an individual visualizes or imagines themselves performing a movement without actually executing it physically. This cognitive process involves the mental rehearsal of motor actions, engaging similar neural pathways that are used when physically performing the action.

Action Observation (AO)

Other

rehabilitation technique based on the principle of observing actions to improve motor function and learning. This approach is rooted in the concept of the mirror neuron system, a group of neurons that are activated both when a person performs an action and when they observe the same action performed by others.

Control condition- placebo

Other

Recording with images of landscapes without the presence of any person or animal that could evoke MI or OA.

Primary outcomes

  1. Disability and Dependence Level - Barthel Index

    Time frame: Administered once, typically taking a few minutes.

    A general measure assessing patient independence, evaluating performance in basic daily activities (ADLs).

  2. Upper Limb Functionality - Action Research Arm Test (ARAT)

    Time frame: Administration time ranges from 5 to 15 minutes.

    Assesses upper limb functionality post-cortical injury, involving manipulation tasks with various objects.

  3. Cognitive Impairment - Montreal Cognitive Assessment (MoCA)

    Time frame: takes about 10 minutes for administration.

    Evaluates mild cognitive dysfunctions across multiple domains, including attention, memory, language, and executive functions.

  4. Perception Impairment - Loewenstein Occupational Therapy Cognitive Assessment (LOTCA)

    Time frame: Duration varies based on the number and type of subtests administered.

    Specific for occupational therapy in stroke patients, assessing visual, spatial, motor, and cognitive perception.

  5. Mental Evocation Ability - Mental Evocation of Images, Movements, and Activities Questionnaire (CEMIMA)

    Time frame: Duration varies

    Measures the ability to mentally form visual and kinesthetic images of the hand/upper limb.

  6. Quality of Life Perception - Stroke Impact Scale 16 (SIS-16)

    Time frame: 5-10 minutes.

    A self-report measure focusing on physical aspects including strength, hand function, mobility, and ADLs.

  7. Electromyographic Activity During MI and AO

    Time frame: during the experimental setup

    muscle activity using surface electrodes on wrist extensors and flexors.

Secondary outcomes

  1. Age

    Time frame: 1 minute

    birth age

  2. gender

    Time frame: 1 minute

    he gender with which the participant identifies

  3. Marital Status

    Time frame: 1 minute

    single, married, divorced

  4. Education Level

    Time frame: 1 minute

    he highest level of education

  5. Economic Status

    Time frame: 1 minute

    participant's economic

  6. Affected Side

    Time frame: 1 minute

    The side of the body affected by the stroke or injury

  7. Dominant Side

    Time frame: 1 minute

    The side of the body that is the participant's natural dominant side

  8. Type of Lesion

    Time frame: 1 minute

    specific type of brain injury

  9. Time Since Injury

    Time frame: 1 minute

    time since the participant had the brain injury or stroke.

Study contacts

Contact information is provided by the study sponsor or research team.

Ana MAría Martín Nogueras, Dr

CONTACT

[email protected]

677510296

Beatriz María Bermejo Gil, Dr

CONTACT

[email protected]

622289468

Sponsors and collaborators

Lead sponsor

University of Salamanca

Other

Registry information

Official study title

Upper Limb Electromyographic Response to Motor Imagery and Action Observation in Acquired Brain Injury Patients.

Important dates

Study start
2024
Primary completion
2026
Study completion
2027
First posted
Jan 30, 2024
Registry last updated
Oct 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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