Emergency Pancreaticoduodenectomy: a Non-trauma Center Case Series

Pancreaticoduodenectomy is a challenging procedure itself, being even more complex and demanding in emergency settings. Only a few cases of emergency pancreaticoduodenectomy (EPD) are reported in medical literature, usually performed for complex pancreaticoduodenal lesions. EPD has first been mentioned in trauma settings, even fewer cases being reported for non-traumatic indications. The investigators intend to present our experience with this intervention, in a non-trauma surgical centre. Our study is a prospective consecutive case series, that included patients that underwent emergency pancreaticoduodenectomy from January 2014 to May 2021. Data was collected from the electronic system database. The investigators collected data regarding the demographic characteristics of the patients, their medical history, preoperative and postoperative investigations (including blood work and imagistic investigations), surgery related information and postoperative evolution.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Emergencies Digestive System Diseases Disease Attributes Pancreas Disease Pancreatic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Emergency pancreaticoduodenectomy performed

Exclusion criteria

Elective surgery
Insufficient data

Treatment and study plan

emergency pancreaticoduodenectomy

Procedure

Emergency pancreaticoduodenectomy (EPD) is a complex surgical procedure, that can be performed for complex pancreaticoduodenal injuries, that cannot be controlled through less invasive procedures. EPD can be performed either as a classical Whipple procedure, or as a pylorus-preserving procedure. A one stage procedure implies the reconstruction step being done in the same surgical intervention, while a two step procedure implies the reconstruction being done in a later stage, through a second surgical intervention.

Primary outcomes

Intraoperative blood loss

Time frame: The length of the surgical intervention (an average of 3 hours)

ml of blood
Operative time

Time frame: The length of the surgical intervention (an average of 3 hours)

minutes of operating time
In-hospital Morbidity

Time frame: Up to 90 days. Through study completion, during the hospital admission period
In-hospital Mortality

Time frame: Up to 90 days. Through study completion, during the hospital admission period
Long-term evolution

Time frame: The date of the last follow-up information was August 2021

It will be measured the overall survival time, number of readmissions and number of reinterventions

Sponsors and collaborators

Lead sponsor

Iuliu Hatieganu University of Medicine and Pharmacy

Other

Registry information

Important dates

Study start: 2014
Primary completion: 2021
Study completion: 2021
First posted: Dec 1, 2021
Registry last updated: Dec 1, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed