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Completed

NCT Number: NCT02973919

EMDR in Spider Phobia: Work Mechanisms and Treatment Outcome

The goal of this study is to increase the efficiency of exposure in virtual reality (VR).

Based on the EMDR research the investigators would like to show that the implementation of eye movements during the VR exposure results in a faster physiological relaxation response among probands with spider phobia, which has a positive effect on the subjective and behavioral efficacy of the VR exposure.

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Key information

Age range

18 year–55 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

The VR paradigm consists of one room with a spider in it. The proband is supposed to look at it for a few minutes. This exposure is repeated several times.

In the experimental group a ball appears during the exposure, that moves horizontally across the room. The probands are supposed to follow this movement with their eyes.

EDA, EKG and respiration are being recorded. Furthermore the subjective and behavioral spider phobia is measured before, during and after the exposure to determine occurring changes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • the Structured Clinical Interview for DSM-IV (SCID, First et al., 2002; applied German translation: Strukturiertes Klinisches Interview für DSM-IV, Achse I, SKID I, Wittchen et al., 1997), in order to get a reliable diagnosis of spider phobia

Exclusion criteria

  • pregnancy
  • current psychopharmacological medication
  • current involvement in psychiatric- or psychotherapeutic treatment
  • cardiovascular or neurological diseases
  • color blindness
  • hearing disorders

Treatment and study plan

Eye Movement Desensitization and Reprocessing therapy

Behavioral

In 1989, Shapiro discovered that while talking about negative life events or thoughts, rhythmic eye movements on a horizontal axis can alleviate the associated vividness and burden (Shapiro, 1989). She established the psychodynamic-behavioral Eye Movement Desensitization and Reprocessing (EMDR) Therapy, which includes the induction of rhythmic eye movements as a central feature. EMDR is regarded as an efficient treatment tool. Several times it has also been successfully applied in the field of specific phobias (de Jongh, ten Broeke, & Renssen, 1999; de Jongh, Holmshaw, Carswell, & van Wijk, 2011; Lapsekili & Yelboga, 2014; Muris, Merckelbach, van Haaften, & Mayer, 1997) and there is a standard protocol for using EMDR on specific fears and phobias (de Jongh, 2015).

virtual reality exposure therapy

Behavioral

Exposure to fear-evoking stimuli is conducted more often in virtual environments using simulators or similar computer-technologies (Virtual Reality Exposure Therapy, VRET). One great advantage of using VR-technologies is that it is possible to create an environment which is highly controllable by its creators. Feared stimuli or scenarios can be varied on individual purposes and presented several times. This facili- tates the practice of exposure-based treatments especially for situations or places diffi- cult to access or requiring a considerable amount of time and/or money (e.g. being in war zones or a passenger on a flight), where in vivo exposures have often not been con- ducted or only in a limited manner (Mühlberger & Pauli, 2011).

Primary outcomes

  1. Change in Behavioral Assessment Test (BAT) in vivo

    Time frame: 5 minutes before, 5 minutes after intervention and during folow up (2 weeks post Intervention)

    expected fear just before getting started and actually present fear just before finishing

Secondary outcomes

  1. Skin Conductance Reactivity (SCR)

    Time frame: during the VR-session

  2. Electrocardiogram (ECG)

    Time frame: during the VR-session

    providing the Heart Rate (HR)

  3. manipulation check electrode below the right eye (M. orbicularis oculi)

    Time frame: during the VR- exposure sessions (5 min x 4 sessions)

    for registering eye movements

  4. Change in Subjective Fear Ratings

    Time frame: 1 min before and during ( each minute) exposure in Virtual Reality

    Subjective Units of Disturbance Scale

Sponsors and collaborators

Lead sponsor

University of Regensburg

Other

Registry information

Important dates

Study start
2015
Primary completion
2015
Study completion
2016
First posted
Nov 28, 2016
Registry last updated
Nov 28, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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