Skip to main content
OpenTrials
Completed

NCT Number: NCT03208972

Elonva in Combination With Hp-FSH Versus Elonva With Low Dose hCG

The study compares in a randomized controlled way two stimulation methods. One of these stimulation methods implements a new insight in ovarian follicular growth. If this novel method of stimulation proves to be as efficient as the classical stimulation protocols, there might be a dramatic reduction of the costs of the medical therapy in IVF, thus reducing also the overall IVf costs significantly.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

18 year–38 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

AZ Jan Palfijn

Ghent, Oost-Vlaanderen, 9000, Belgium

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • IVF/ICSI patients
  • Cycle 1, 2, 3, 4

Exclusion criteria

  • PCOS
  • Endocrinological diseases

Treatment and study plan

Low dose HCG

Drug

Other names: Pregnyl

hp-FSH

Drug

Other names: Menopur

Corifollitropin alfa

Drug

Corifollitropin Alfa (Elonva) dosage depending on weight, once administered first day of ovarian stimulation for all subjects, and on day 7 they proceed with the treatment of the allocated group.

<60 kg: Elonva 100 MCG > 60 kg: Elonva 150 MCG

Other names: Elonva

Primary outcomes

  1. The financial costs of the stimulation in both groups

    Time frame: 1 year

Secondary outcomes

  1. The number of MII oocytes obtained at the occasion of the oocyte retrieval

    Time frame: 3 weeks

  2. pregnancy rate

    Time frame: 5 weeks

  3. duration of the stimulation

    Time frame: one month

  4. hormonal levels reached at time of induction of final maturation of the oocyte

    Time frame: 3 weeks

  5. the number of clinical OHSS patients

    Time frame: one month

Sponsors and collaborators

Lead sponsor

AZ Jan Palfijn Gent

Other

Collaborators

  • Onze Lieve Vrouw Hospital

Registry information

Official study title

Prospective Randomized Trial Comparing Ovarian Stimulation in IVF-patients With Corifollitropin Alfa in Combination With Hp-FSH Versus Corifollitropin Alfa in Combination With Low Dose hCG

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Jul 6, 2017
Registry last updated
Feb 3, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.