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Completed

NCT Number: NCT04427748

Electrophysiology in Congenital Cataract After Lensectomy and Anterior

In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test group, 25 normal eyes as control group. The a- and b-wave and PhNR related parameters was evaluated.

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Key information

Conditions

Congenital Cataract

Age range

18 month–15 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Eye Hosptial of Wenzhou Medical College

Wenzhou, Zhejiang, 325027, China

About this study

Secondary IOL implantation in aphika children and lensectomy and anterior vitrectomy and primary IOL implantation in children with congenital cataract were both performed by the same surgeon(Z.Y.E).

electroretinography and photopic negative response are performed to each patient.The research was to evaluate the relationship between the best corrected visionn and the related parameters of a- and b-wave and PhNR .

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • phakic children diagnosed with congenital cataract who underwent secondary IOL implantation and children with congenital cataract who underwent lensectomy and anterior vitrectomy and primary IOL implantation

Exclusion criteria

  • patients with mild cataracts do not require surgery

Treatment and study plan

Primary outcomes

  1. ERG

    Time frame: at least 1year after the surgery of congenital cataract

    investigate retinal function changes of congenital cataract children. ERG related parameters including a- and b-wave and PhNR amplitude and latency.

Sponsors and collaborators

Lead sponsor

Wenzhou Medical University

Other

Registry information

Official study title

The Change of Electrophysiology in Congenital Cataract After Lensectomy and Anterior Vitrectomy

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Jun 11, 2020
Registry last updated
Jun 11, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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