Electrophysiological Signatures of Distinct Working Memory Subprocesses That Predict Long-term Memory Success

Healthy young adults will view pictures of items while the investigators record electroencephalogram (EEG) brain activity. Then, the investigators will ask the participants to report which items the participants remember seeing. The investigators will examine how the measured brain activity relates to which pictures the participants remember.

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Key information

Conditions

Memory EEG

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Chicago

Chicago, Illinois, 60637, United States

About this study

Electrophysiological signatures track distinct subprocesses of working memory, including the number of items and the spatial locations of those items. By identifying how these subprocesses predict long-term memory success in healthy young adults, this project should lead to an intricate understanding of the relationship between working memory and long-term memory. This study will investigate when and how long-term memory failures arise, by using sophisticated machine learning analyses of neural data. Moreover, this study will test the extent to which the investigators can track working memory processes in real time and how the investigators can leverage that information to improve long-term memory success. This will inform basic theories of the relationship between working memory and long-term memory and motivate future applications.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

normal or corrected to normal vision

Exclusion criteria

non-fluent in English

Treatment and study plan

No intervention

Other

There is no intervention

Primary outcomes

Memory performance

Time frame: This task is performed multiple time within the experimental session, which in total lasts around 3 hours.

To measure recognition memory performance, participants will view pictures and respond as to whether they remember previously seeing these items. Participants will be shown both old and new items. In the long-term memory phase, they will report their confidence at having seen each image using a four point rating scale, ranging from being confident the item is new (i.e., not previously seen) to being confident the item is old (i.e., previously seen).

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Registry information

Acronym: WMLTM

Important dates

Study start: 2022
Primary completion: 2024
Study completion: 2026
First posted: Jun 7, 2023
Registry last updated: Jun 9, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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