University Hospital of Larissa
Larissa, Thessaly, 41110, Greece
NCT Number: NCT02036346
One of the main reasons for hospital readmission in ileostomy patients is fluid and electrolyte abnormalities. Prospective observational studies have suggested an occurrence rate of around 20%. Due to colonic exclusion ileostomy patients lose large amounts of sodium and fluid through their stoma effluent. In addition studies have shown that ileostomy construction is a risk factor for renal impairment, occurring secondary to dehydration.
Encouraging patients to increase total fluid intake seems to be a common mistake in clinical practice as this can dilute sodium levels even more, causing greater sodium depletion. In terms of addressing the problem a few small studies have used isotonic drinks of various compositions showing increased electrolyte absorption.
Other dietary complications sometimes include hypomagnesaemia and decreased absorption of B-12 and folic acid, however due to the integrity of the small intestine other nutrient malabsorption is unlikely to occur. As far as body composition is concerned obesity has been shown to be a risk factor for peri- and postoperative complications in colorectal surgery (e.g. peristomal dermatitis, stoma stenosis and prolapse). A prospective trial examining measures that can prevent readmission for dehydration and other nutritional considerations related to this group of patients is definitely required.
Hypothesis:
The administration of an oral rehydration solution will allow a significant decrease in dehydration and electrolyte abnormality rates in patients with a temporary ileostomy.
Looking for future studies?
Notify Me18 year and older
All sexes
Interventional
Not applicable
Larissa, Thessaly, 41110, Greece
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Oral rehydration solution containing: sodium chloride, sodium citrate, glucose, magnesium citrate, food additives and water.
Time frame: up to 20-40 days postoperatively
sodium (mmol/l)
Time frame: up to 20-40 days postoperatively
potassium (mmol/l)
Time frame: up to 20-40 days postoperatively
magnesium (mg/dl)
Time frame: up to 20-40 days postoperatively
chloride (mmol/l)
Time frame: 20 days postoperatively, 40 days postoperatively
thirst, dizziness, lethargy, oliguria, dense urine
Time frame: 20 days postoperativey, 40 days postoperatively
Urea (mg/dl)
Time frame: 20 days postoperativey, 40 days postoperatively
Creatinine (mg/dl)
Time frame: baseline, 40 days postoperatively
weight (kg)
Time frame: baseline, 40 days postoperatively
height (m)
Time frame: baseline, 40 days postoperatively
BMI (kg/m2)
Time frame: baseline, 40 days postoperatively
total body fat (%)
Time frame: baseline, at 20 days and 40 days postoperatively
Energy intake assessed through 24hour recalls and analyzed via nutrition analysis software
Time frame: baseline, at 20 days and 40 days postoperatively
Macronutrient intake assessed through 24hour recalls and analyzed via nutrition analysis software
Time frame: baseline, at 20 days and 40 days postoperatively
Electrolyte intake via diet assessed through 24hour recalls and analyzed via nutrition analysis software
Time frame: baseline, at 20 days and 40 days postoperatively
Larissa University Hospital
Other
The Effect of Ileostomy Formation on Nutritional Status and Electrolyte Profile in Rectosigmoidectomy Patients: a Prospective Randomized Trial.
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