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Enrolling by Invitation

NCT Number: NCT07394634

Efficiency of Self Extracted Tooth Graft in Extraction Socket : A Clinical and Radiographic Study

This is the clinical trial. The goal of this clinical trial is to test whether self extracted tooth graft (autogenous tooth graft ) able to preserved the extraction socket effectively. Our aim is to answer is there any difference in dimensional changes in extraction socket in clinically and radiographically Researchers will compare autogenous tooth graft with self-healing extraction socket in radiographic and clinical measurement.

Participant will be randomly allocated into 2 groups ( Test or controlled group) Test group will be autogenous tooth grafting post extraction. After removed any caries, calculus and any gilling material, the extracted tooth will be grind with grinder and processed using BONMAKER machine. (which the bone graft is washed with hydrogen peroxide, hydrogen chloride and alcohol isopropyl) and controlled group will be self healing group. Both group will withdraw 20cc blood for PRF ( Plasma rich fibrin) membrane and place into the socket and secured with suture. They will be reviewed post extraction 1 week ( to ensure there is no infection ) , 2 week ( for suture removal ) , 1 months ( For clinical measurement) , 3 months (For clinical and radiographic measurement) and 6 months (For radiographic measurement).

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Key information

Conditions

Healthy

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistrty

Jenjarum, Selangor, 42610, Malaysia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age> or equal to 18 years old
  • Presence of adjacent teeth to the extraction site
  • Healthy ,or well controlled systemic disease
  • Lower and upper incisors, lower premolar/ first molar
  • Full mouth plaque score < 15%
  • Adequate space for a dental implant restoration *Patient with previous diagnosis of periodontitis will be required to have a successfully completed course of periodontal treatment before enrolment.

Exclusion criteria

  • Smokers and vapers
  • Acute infection or sinus tract in relation to the tooth that require extraction
  • Pregnant or lactating women
  • Patient received antibiotic for past 1 month
  • Loss of more than 50% buccal or lingual /palatal bone at the time of extraction
  • Patient on medication that altered bone metabolism or bone healing such as bisphosphonates, chemotherapeutic drugs or immunosuppressive agents

Treatment and study plan

autogenous tooth graft

Procedure

Extracted tooth will be grind and processed into bone graft . This bone graft material will grafted into the extraction socket

Primary outcomes

  1. Socket dimensional changes in autogenous tooth graft group and self healing group

    Time frame: 6 months

    Socket dimensional changes will be measure in clinical and radiographic measure Clinical measure: A stent will be made prior extraction and hole on the stent will be made to standardized measurement. Clinical measurement ( socket height) will be measure during post extraction, 1 month, 3 month and 6 month to observe the value of the resorption of the extraction socket . The discrepancy value is will be from ( 1month -baseline, 3month-baseline, 6month- baseline)

    Radiographic measure: CBCT will be taken post extraction 3 month and 6month. Socket width will be measure in 3mm below the socket and 5 mm below the socket. Other than that, mimic software will be used for the volumetric changes.

Secondary outcomes

  1. Volumetric changes in autogenous tooth group and self healing group

    Time frame: 6 months

    In this , mimic software will be used for volumetric changes

Sponsors and collaborators

Lead sponsor

Mahsa University

Other

Registry information

Official study title

Evaluating the Efficacy of Autogenous Tooth Graft (ATG) Material in Socket Preservation: A Clinical and Radiographic Study.

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 6, 2026
Registry last updated
Feb 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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