Skip to main content
OpenTrials
Completed

NCT Number: NCT02297165

Efficacy Study of an Olfactory Stimulation Program for the Recuperation of Autobiographical Memories in Anorexia

The purpose of this study is to estimate the impact of an olfactive stimulation, in relaxing environment, on the access at the autobiographical memories in anorexic patients.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Anorexic Anorexia Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

13 year–24 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Groupement des Hôpitaux de l'Institut Catholique de Lille

Lille, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Eating disorders, anorexia (restrictive form or mixed) according to DSM IV-TR ( Diagnostic and Statistical Manual of Mental Disorders IV - Text Revision) criteria
  • Patient hospitalized in a department of one of the inquiring centers for a minimal duration of 5 weeks
  • French language ability
  • Coverage by the social insurance
  • Fully informed patient who consent to participate in the study

Exclusion criteria

  • Major mental associated disorders (psychotic disorders, bipolar disorder, major depression), neurological disorders or addiction to substances
  • Psychotropic treatment (with the exception of antidepressants, anxiolytics and sleeping drugs, if the treatment was started more than 30 days ago)
  • Any disorder susceptible to alter the reasoning capacities, discernment or judgment
  • Physically or psychologically unable to answer questionnaires

Treatment and study plan

olfactory stimulation program

Behavioral

8 individual sessions of olfactory stimulation at the rate of 2 sessions per week. 3 semi-directed interviews will be help (one at the beginning of the trial, the second 5 weeks later and the third at 6 month).

For each session, patients have to smell two different odors (previously selected from a panel presented to the patient during first visits) and then they are invited to evoke memories and feelings related to each odor.

Primary outcomes

  1. Proportion of reminded specific autobiographical memories (Autobiographical Memory Test (AMT)

    Time frame: After 5 weeks

    Autobiographical Memory Test (AMT) at inclusion and 5 weeks after

Secondary outcomes

  1. Body mass index

    Time frame: first day of enrollment and 5 weeks after

    Evaluation of size and weight

  2. Evaluation of the specific memories recovery stimulation on the emotional differentiation ability (Level of Emotional Awareness Scale (LEAS)

    Time frame: first day of enrollment and 5 weeks after

    Level of Emotional Awareness Scale (LEAS)

  3. Evaluation of mental rumination (Cambridge Exeter Rumination Thinking Scale)

    Time frame: first day of enrollment and 5 weeks after

    Cambridge Exeter Rumination Thinking Scale

  4. Evaluation of anxiety and depression (Hospital Anxiety and Depression Scale)

    Time frame: first day of enrollment and 5 weeks after

    Hospital Anxiety and Depression Scale

  5. Evaluation of eating behaviors (Eating Disorder Inventory)

    Time frame: first day of enrollment and 5 weeks after

    Eating Disorder Inventory

  6. Evaluation of history of abuse (Childhood Trauma Questionnaire)

    Time frame: first day of enrollment and 5 weeks after

    Childhood Trauma Questionnaire

  7. Evaluation of cognitive avoidance strategies (Questionnaire of cognitive avoidance)

    Time frame: first day of enrollment and 5 weeks after

    Questionnaire of cognitive avoidance

Sponsors and collaborators

Lead sponsor

Lille Catholic University

Other

Registry information

Official study title

Efficacy Study of an Olfactory Stimulation Program in Relaxing Environment for the Recuperation of Autobiographical Memories in Anorexic Patients

Acronym: OLFANOR

Important dates

Study start
2014
Primary completion
2017
Study completion
2018
First posted
Nov 21, 2014
Registry last updated
Apr 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.