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OpenTrials
Completed

NCT Number: NCT00437255

Efficacy, Safety, Preference and Response Duration of Clobex® Spray and Taclonex® Ointment in Psoriasis

Evaluate the efficacy of Clobex® Spray as compared to Taclonex® Ointment in terms of Overall Disease Severity and Investigator Global Assessment.

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Key information

Conditions

Plaque Psoriasis

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Minnesota Clinical Study Center, Fridley, Minnesota, United States

Loading trial locations.

About this study

Same as above.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Moderate to severe psoriasis involving 3-20% of the body surface area

Exclusion criteria

  • Subjects who have surface area involvement too large that would require more than 50 grams per week of Clobex® Spray or more than 100 grams per week of Taclonex® Ointment
  • Subjects having psoriasis that involves the scalp, face, or groin

Treatment and study plan

Clobetasol Propionate, 0.05%

Drug

Topical, twice daily for 4 weeks

Other names: Clobex® Spray

Calcipotriene and betamethasone dipropionate ointment

Drug

Topical, once daily

Other names: Taclonex® Ointment

Primary outcomes

  1. Overall Disease Severity

    Time frame: End of treatment (Week 4)

  2. Tolerability assessments, incidence of adverse events

    Time frame: Baseline, Weeks 1, 2, 4 and 8

Secondary outcomes

  1. Overall Disease Severity

    Time frame: Weeks 1, 2 and 8

  2. Investigator Global Assessment

    Time frame: End of treatment (week 4) and Weeks 1, 2 and 8

Sponsors and collaborators

Lead sponsor

Galderma R&D

Industry

Registry information

Official study title

An Evaluation of the Efficacy, Safety, Preference and Duration of Response of Clobex® (Clobetasol Propionate) Spray and Taclonex® (Calcipotriene 0.05%/Betamethasone Dipropionate 0.064%) Ointment in Subjects With Stable Plaque Psoriasis

Important dates

Study start
2006
Primary completion
2007
Study completion
2007
First posted
Feb 19, 2007
Registry last updated
Jul 29, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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