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NCT Number: NCT06585852

Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement

The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.

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Key information

Conditions

Implant Dentistry

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Al Azhar University of Cairo

Cairo, Nasr City, Egypt

Location status: Recruiting

Location contact

Ibrahim Sabri, PHD

CONTACT

+20 100 780 9113

Mahmoud El Destawy, PHD

CONTACT

+201225864104

About this study

A comparative study for ridge augmentation procedure, With two groups. First group underwent a surgical ridge splitting procedure with ultrasonic bone surgery and grafting with Xenograft alone and implant placement. Second group underwent a surgical ridge splitting procedure with ultrasonic bone surgery Xenograft mix ed with Arginylglycylaspartic acid (RGD) and implant placement.

Both groups were followed up for 1 and 3 months after loading.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (age 18-30) exhibiting initial insufficiently bone width.
  • Patients with good oral hygiene.
  • Patients must be free from systemic diseases that may influence the outcome of the therapy.
  • Patients with bony horizontal defects alone, Class III & IV.

Exclusion criteria

  • Heavy smokers.
  • Patient treated by immunosuppressive chemotherapy or radio therapy,
  • Allergy to any material or medication used in the study.
  • Pregnant females.

Treatment and study plan

RGD

Drug

Study group main material

Other names: Arginylglycylaspartic acid

Xenograft

Drug

Scaffold material of choice

Split crest technique

Procedure

Piezoelectric surgery

Primary outcomes

  1. ISQ measurement for implant stability

    Time frame: At time of surgery, at loading and 3 months after loading.

    Evaluate implant stability by osstell device

Secondary outcomes

  1. Bone density around dental implants.

    Time frame: At time of loading and 3 months after loading

    Evaluation of bone density after ridge splitting and implant placement

Study contacts

Contact information is provided by the study sponsor or research team.

Ibrahim Sabri

CONTACT

[email protected]

01007809113

Mahmoud Taha, PHD

CONTACT

[email protected]

01225864104

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement. A Randomized Clinical Trial

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 19, 2024
Registry last updated
Sep 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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