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NCT Number: NCT06960915

Efficacy of Virtual Reality Reminiscence Therapy in Nursing Home Residents With Alzheimer's Disease or Related Diseases

This project provides the easiest possible access to heritage elements that older persons with Alzheimer's disease or related diseases knew well but to which they no longer have access due to the motor and functional dependencies they present. It will strengthen the possibilities of reminiscence by using, rather than the usual supports, virtual reality technology to reinforce the immersion effect. It will involve carrying out virtual reality reminiscence workshops intended for residents in nursing home with Alzheimer's disease or related diseases and allowing them to explore the heritage of towns and villages in the Somme region thanks to these innovative solutions. The aim of this project is to reduce behavioral disorders and improve their quality of life.

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This study is active but is not currently recruiting participants.

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Key information

Conditions

Virtual Reality Alzheimer's Disease or Related Diseases Crossover Study Nursing Home Reminiscence Therapy

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHRU Amiens

Amiens, 80480, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Residents of the long-term care facilities of the Amiens-Picardie University Hospital,
  • Residents with mild to moderate Alzheimer's disease or related diseases, i.e. with an MMSE ≥ 10,
  • Residents or their legal representative agreeing to participate in the study.

Exclusion criteria

  • Non-residents of the long-term care facilities of the Amiens-Picardie University Hospital,
  • Residents with an MMS < 10,
  • Residents or their legal representative refusing to participate in the study,
  • Residents in terminal palliative care,
  • Residents with disruptive behavioral disorders.

Treatment and study plan

immersive virtual reality

Device

The research procedure will be the realization of reminiscence workshops in immersive virtual reality. The residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc.

classic reminiscence workshops

Device

It will be compared to classic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm.

Primary outcomes

  1. Reduced behavioral problem frequency in immersive virtual reality group

    Time frame: 1 year

    Efficacy in reducing behavioral problems will be assessed using the sum of scores on the NPI-ES anxiety, depression, and apathy subscales.

Secondary outcomes

  1. Improved quality of life in the immersive virtual reality group

    Time frame: 1 year

    improving the quality of life will be assessed using a quality of life scale developed for patients with Alzheimer's disease or related diseases, the QOL-AD scale validated in French.

    The QOL-AD is administered in interview format to individuals with dementia, following the instructions below.

    Scoring instructions for QOL-AD:

    Points are assigned to each item as follows: poor = 1, fair = 2, good = 3, excellent = 4.

    The total score is the sum of all 13 items.

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Acronym: ReminiSOMME

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
May 7, 2025
Registry last updated
Feb 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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