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OpenTrials
Completed

NCT Number: NCT06847022

Efficacy of US-guided TFPB in Open Gynecologic Surgery

Transversalis fascia plane block (TFPB) has been studied and has shown to be very effective in controlling postoperative pain after caesarean section but has not been studied in open gynecologic surgery with transverse incision. Inadequate pain control after open gynecologic surgery is associated with negative consequences such as chronic pelvic pain. The investigators aimed to evaluate the efficacy of TFPB in controlling postoperative pain after open gynecologic surgery with transverse incision.

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Key information

Conditions

Transversalis Fascia Plane Block Gynecologic Surgical Procedures

Age range

18 year–70 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anesthesiology, Faculty of Medicine, Thammasat University

Pathum Thani, 12121, Thailand

About this study

A randomized controlled trial study in which comparing US-guided TFPB vs conventional pain control in open gynecologic surgery

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who undergoing open gynecologic surgery under general anesthesia
  • Age 18 - 70 years
  • ASA Physical status I-III
  • Transverse incision

Exclusion criteria

  • Creatinine clearance is less than 30 ml/min
  • Body weight < 50 kg
  • Re-open surgery
  • Persistent chronic pelvic pain
  • Allergic to medications used in this study

Treatment and study plan

US-guided transversalis fascia plane block

Procedure

US-guided bilateral transversalis fascia plane block, using Sonotap 110 mm and 0.25% bupivacaine 20 ml on each side, will be done after wound closure.

Primary outcomes

  1. Postoperative 24 hours morphine requirement

    Time frame: 24 hours

Secondary outcomes

  1. postoperative pain score

    Time frame: 1 hour, 6 hours, 24 hours

  2. Side effects from postoperative opioids

    Time frame: 24 hours

    nausea vomiting, itching, respiratory depression

  3. Incidence of chronic pelvic pain

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Thammasat University

Other

Registry information

Official study title

Efficacy of Ultrasound-guided Transversalis Fascia Plane Block (TFPB) in Controlling Postoperative Pain After Transverse Incision in Gynecologic Surgery

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Feb 26, 2025
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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