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NCT Number: NCT02890771

Efficacy of Turmeric in Gingival Massaging and Adjunct to Scaling and Root Planing in Chronic Periodontitis Patient

Periodontal disease is considered as inflammatory, multifactorial, and threshold disease accompanied by destruction of periodontium and eventually the loss of natural teeth. Periodontal disease is highly prevalent dental disease especially, in developing and underdeveloped countries affecting more or less 80% of the population. For the prevention of this highly prevalent dental affliction, still no effective and practical preventive measures are available which can reduce its high prevalence rate though, lot of research work is going on.

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Key information

About this study

Various interceptive and therapeutic modalities are available comprising of non-surgical and surgical therapies. But, these therapies are not available for everyone, due to various reasons such as low socio-economic conditions of the majority of the population including poverty, illiteracy, and malnutrition etc. along with low dentist: population ratio. Moreover, the availability of a dentist and/or periodontist is limited in rural and remote areas, whereas the prevalence rate of periodontal disease is comparatively higher in these areas than that of urban areas.

Looking to these difficulties, the investigators have to think and explore the beneficial effects by conducting research work on various home care measures which are being used since many generations, especially in our country and thus people were/are enjoying the benefits with almost all or many natural teeth, up to last span of their lives.Though, the scientific evidences of beneficial effects of home care measures for cleaning and massaging of teeth and gums, respectively are not yet evident significantly. But, traditional uses of various dentifrices those are still in practices and thus need scientific attentions. Now, the investigators are in the evidence based era, especially in the field of medical sciences. Therefore, the number of research studies should be planned and carried out at various centres in different parts of the country, to ascertain the beneficial effects of traditional oral hygiene practices such as: Datoons (Neem, Babool etc), leaves of various plants like Mango, Charcoal powder, Meswak, salt, Mustard oil with Salt, and Turmeric powder and other such home care dental cleansing materials. After getting the beneficial information's/evidences accordingly, the uses of specific traditional materials and methods for the cleansing of the teeth and massaging of the gums can be advocated. And thus, specifically the developing and underdeveloped countries may be benefitted.

Out of various home care dental cleansing materials the Turmeric powder is not only being used as one of important condiments of our kitchen, and at the same time as a medicinal use since ages.

The 'Turmeric' is known for its anti-inflammatory, antioxidant, antimicrobial, immune stimulant, antiseptic, anti-carcinogenic, and anti-mutagenic properties [1]. Drake [2] and Han et al [3], observed anti- microbial activity of Turmeric. Roobal Bahal et al [4] stated that on use of 2% Turmeric gel, significant reduction in the mean plaque index, gingival index, sulcus bleeding index, probing pocket depth and significant reduction in trypsin like enzymatic activity of "Red-Complex" microorganisms. Ruchika Jaswal et al [5] conducted a pilot study to evaluate and compare the clinical effects of topical subgingival application of 2% whole turmeric gel and 1% chlorhexidine gel as an adjunct to scaling and root planing (SRP) in patients suffering from chronic periodontitis.

Very few studies, which can be counted on fingers, have been conducted worldwide in this direction. Hence, this study is being taken to evaluate the efficacy of whole Turmeric Powder in Gingival Massaging and as an adjunct to Scaling and Root Planing in Patients with Chronic Periodontitis.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Cases with moderate to severe form of Generalized Chronic Periodontitis patients of any sex.
  • Patients in the age group of 35-65 years, who abide by approved protocol guidelines, and are ready to give written informed consent.

Exclusion criteria

  • Any known systemic disease which has effects on periodontium such as diabetes etc.
  • Patients on anti-inflammatory, antibiotics and perioceutics, since 3 months.
  • Patients who have known allergy to material used for the study.
  • Pregnant and lactating mothers.
  • Patients had undergone any kind of non-surgical and/or surgical periodontal therapy earlier, in past 6 months.
  • Tobacco users.

Treatment and study plan

Tooth Brushing with Dentifrice

Procedure

Tooth Brushing with Dentifrice (Standard Tooth Brushing technique will be demonstrated by using same type of tooth brush and toothpaste).

Turmeric Massaging

Procedure

:-Tooth Brushing with Dentifrice (with same type of tooth brush and toothpaste) and massaging with whole Turmeric Powder.

SRP with turmeric massaging

Procedure

on one side of the arch only Scaling and Root Planing(SRP) to be done, while on the other side, after the Scaling and Root Planing massaging with whole Turmeric Powder shall be carried out by the patients/subjects

Primary outcomes

  1. Plaque Index (Turesky modification of Quigley Hein Index, 1970)

    Time frame: baseline

Secondary outcomes

  1. Plaque Index (Turesky modification of Quigley Hein Index, 1970)

    Time frame: 1 week

  2. Plaque Index (Turesky modification of Quigley Hein Index, 1970)

    Time frame: 2 week

  3. Plaque Index (Turesky modification of Quigley Hein Index, 1970)

    Time frame: 4 week

  4. Plaque Index (Turesky modification of Quigley Hein Index, 1970)

    Time frame: 6 week

  5. Gingival Index (Loe H and Silness J 1963)

    Time frame: baseline

  6. Gingival Index (Loe H and Silness J 1963)

    Time frame: 1 week

  7. Gingival Index (Loe H and Silness J 1963)

    Time frame: 2 week

  8. Gingival Index (Loe H and Silness J 1963)

    Time frame: 4 week

  9. Gingival Index (Loe H and Silness J 1963)

    Time frame: 6 week

  10. Russell's Periodontal Index (Rusell's A.L, 1956)

    Time frame: baseline

  11. Russell's Periodontal Index (Rusell's A.L, 1956)

    Time frame: 1 week

  12. Russell's Periodontal Index (Rusell's A.L, 1956)

    Time frame: 2 week

  13. Russell's Periodontal Index (Rusell's A.L, 1956)

    Time frame: 4 week

  14. Russell's Periodontal Index (Rusell's A.L, 1956)

    Time frame: 6 week

  15. Periodontal Probing Depth

    Time frame: baseline

  16. Periodontal Probing Depth

    Time frame: 1 week

  17. Periodontal Probing Depth

    Time frame: 2 week

  18. Periodontal Probing Depth

    Time frame: 4 week

  19. Periodontal Probing Depth

    Time frame: 6 week

  20. Clinical Attachment Levels

    Time frame: baseline

  21. Clinical Attachment Levels

    Time frame: 1 week

  22. Clinical Attachment Levels

    Time frame: 2 week

  23. Clinical Attachment Levels

    Time frame: 4 week

  24. Clinical Attachment Levels

    Time frame: 6 week

Sponsors and collaborators

Lead sponsor

Government College of Dentistry, Indore

Other

Registry information

Official study title

To Evaluate the Efficacy of Whole Turmeric Powder in Gingival Massaging and as an Adjunct to Scaling and Root Planing in Patients With Chronic Periodontitis

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Sep 7, 2016
Registry last updated
Mar 15, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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