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Completed

NCT Number: NCT00175617

Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss

This study evaluates the efficacy of therapy with the anti-androgen spironolactone compared to topical minoxidil in female pattern hair loss.

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Key information

Conditions

Female Pattern Hair Loss

Age range

18 year–75 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 2

Primary location

UBC Division of Dermatology, Hair Research and Treatment Centre

Vancouver, British Columbia, V6G 1Y6, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects must be premenopausal women older than 18 with female pattern hair loss.

Exclusion criteria

  • Androgen excess
  • Other scalp or hair disorders
  • Contraindications to spironolactone treatment, especially pregnancy, electrolyte imbalances, history of breast cancer, or intake of interfering drugs
  • Contraindications to minoxidil treatment, especially patients who are allergic to this treatment or have a history of low blood pressure or irregular heart beats

Treatment and study plan

Spironolactone

Drug

This study evaluates the efficacy of therapy with the anti-androgen spironolactone compared to topical minoxidil in female pattern hair loss.

minoxidil

Drug

This study evaluates the efficacy of therapy with the anti-androgen spironolactone compared to topical minoxidil in female pattern hair loss.

Primary outcomes

  1. hair density

    Time frame: after 3, 6 and 9 months

Secondary outcomes

  1. percentage of subjects who experience side effects

  2. subject assessment of treatment effect

Sponsors and collaborators

Lead sponsor

University of British Columbia

Other

Registry information

Official study title

Efficacy of Therapy With the Anti-androgen Spironolactone Compared to Topical Minoxidil in Female Pattern Hair Loss

Important dates

Study start
2005
Primary completion
2009
Study completion
2009
First posted
Sep 15, 2005
Registry last updated
Mar 3, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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