Skip to main content
OpenTrials
Recruiting

NCT Number: NCT05821075

Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy

Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies.

Many patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Bell Palsy Cranial Nerve Diseases DNA Virus Infections Facial Nerve Diseases Herpesviridae Infections Infections Mouth Diseases Nervous System Diseases Stomatognathic Diseases Virus Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

October 6 university hospital

Giza, 12573, Egypt

Location status: Recruiting

Location contact

Abdelmaksod Mohammed Mousa, MD

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • unilateral acute facial palsy of no identifiable cause

Exclusion criteria

  • Recurrent facial Bell's palsy
  • Pregnancy
  • Diabetes
  • Epilepsy
  • Severe hypertension,
  • Renal or hepatic disease,
  • Gastric or duodenal ulcer
  • presence of acute otitis media or ipsilateral chronic otitis
  • Recent head injury,
  • psychiatric disease
  • If there is any contraindications for corticosteroids

Treatment and study plan

Prednisolone

Drug

prednisolone 60mg tablet once daily for 5 days then tapering dose

Cerebrolysin

Drug

intramuscular Cerebrolysin 10 mg daily for 3 weeks

Primary outcomes

  1. change in scores of the house Brackman grading system HB

    Time frame: at baseline, after 1 week, after 3 week

  2. changes in scores of the Sunnybrook grading system.

    Time frame: at baseline, after 1 week, after 3 week

Study contacts

Contact information is provided by the study sponsor or research team.

Engy Wahsh

CONTACT

[email protected]

01003095692

mohamed rez

CONTACT

[email protected]

01006904056

Sponsors and collaborators

Lead sponsor

October 6 University

Other

Registry information

Official study title

Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Apr 20, 2023
Registry last updated
Jul 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.