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Completed

NCT Number: NCT00572104

Efficacy of Plyometrics to Increase Bone Mass in Men With Osteopenia

This study will compare the ability of two types of long term (12 months) weight-bearing exercise treatments (1. high-intensity jumping and 2. weight lifting) to increase bone mass of the total body, spine and hip in physically active men with osteopenia.

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Key information

Conditions

Osteopenia Bone Diseases Bone Diseases, Metabolic Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases

Age range

25 year–60 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University of Missouri-Columbia; McKee Gym

Columbia, Missouri, 65211, United States

About this study

The overall goal of this project is to determine the efficacy of chronic (12 months) plyometric jump training exercise on bone mineral density (BMD) and markers of bone turnover in physically active males cyclists diagnosed with osteopenia below normal bone mineral density of the lumbar spine or hip.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male
  • Age 25-60 years
  • No symptoms of disease
  • Currently participating in cycling activities an average of 4 hr/wk for the previous 24 months
  • Osteopenia of the lumbar spine and/or hip (T score < -1.0 and > -2.5 )

Exclusion criteria

  • Medications or supplements that affect bone metabolism or prevent exercise
  • Previous or current medical condition affecting bone health
  • Osteoporosis of the lumbar spine and/or hip (T score > -1.0 or < -2.5)
  • Cardiovascular disease
  • Metallic implants
  • Current smoker
  • Current regular participation in high-intensity resistance training and/or plyometrics

Treatment and study plan

Resistance Exercise

Other

12 month training intervention of weight resistance exercise. All participants receive a daily calcium and vitamin D supplement

Plyometric Exercise

Other

12 month training intervention of plyometric exercise. All participants receive a daily calcium and vitamin D supplement

Primary outcomes

  1. Bone Mineral Density

    Time frame: 12 months

Secondary outcomes

  1. Serum markers of bone turnover

    Time frame: 3 months

  2. Serum hormones regulating bone turnover

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

University of Missouri-Columbia

Other

Collaborators

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  • National Institutes of Health (NIH)

Registry information

Important dates

Study start
2008
Primary completion
2013
Study completion
2013
First posted
Dec 12, 2007
Registry last updated
Oct 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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