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Active, Not Recruiting

NCT Number: NCT07044141

Efficacy of Oral Tofacitinib in Combination of Narrow Band UVB in Treatment of Vitiligo

20 patients will be enrolled. All were given narrowband UVB . 10 wil be give oral azathriopfine . 10 will be given tofacitinib

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Vitiligo Hypopigmentation Pigmentation Disorders Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Lahore general.hospital

Lahore, Punjab Province, Pakistan

About this study

Total 20 patients will be enrolled. All were given narrowband UVB . 10 wil be give oral azathriopfine 50mg twice daily. 10 will be given tofacitinib 5mg twice daily. For 6 months

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patient of vitiligo with any VASI both genders 18 to 60yrs

Exclusion criteria

  • pregnancy/lactation Hyerlipidrmia Patient on immunemodulator Histry pf tuberculosis Immunocompromised patients

Treatment and study plan

azathioprine

Drug

azathioprine 50mg twice daily will be given

tofacitinib

Drug

It is a janus kinase inhibitor

Primary outcomes

  1. VASI improvement upto 50%

    Time frame: 6 months

    Study will be considered efficacious if 50% improvement in VASI from baseline is seen by end of 6 months of study

Sponsors and collaborators

Lead sponsor

Lahore General Hospital

Other Gov

Registry information

Official study title

Efficacy of Oral Tofacitinib in Combination With Narrow Band UVB in the Treatment of Vitiligo

Acronym: NB-UVB

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 29, 2025
Registry last updated
Jun 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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