Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study

The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.

Completed

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Key information

Conditions

Knee Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Rheumatic Diseases

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR)
radiographic confirmed knee OA according to the Kellgren & Lawrence scale

Exclusion criteria

acute septic arthritis
inflammatory arthritis
any other type of arthritis
history of knee buckling or recent knee injury
lack of physical or mental bility to perform or comply with the treatment procedure
diabetes mellitus
fibromyalgia or other chronic pain syndromes
concurrent anti-coagulant/anti-platelet drugs
arthroscopy or intra-articular injections in the previous 3 months

Treatment and study plan

Methylsulfonylmethane (MSM)

Dietary Supplement

Primary outcomes

WOMAC questionnaire

Sponsors and collaborators

Lead sponsor

Assaf-Harofeh Medical Center

Other Gov

Registry information

Important dates

First posted: Aug 25, 2010
Registry last updated: Aug 25, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed