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Completed

NCT Number: NCT03617289

Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department

To determine if magnesium sulfate paired with an analgesic medication will improve patient pain from renal colic compared with analgesic alone.

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Key information

Conditions

Renal Colic Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age >18 years old and <100 years old.
  • Patients seen in the Emergency Department at Henry Ford Macomb hospital.
  • Patients that are A+Ox3.
  • Patients who have typical presentation for renal colic.

Exclusion criteria

  • Age <18 years.
  • Patients with a history of dementia, acute delirium or altered mental status.
  • Patients with inability to consent to study or inability to fill questionnaire independently.
  • Patients with chronic kidney disease and allergies to study drugs.
  • Patients that are pregnant (women who are of child-bearing potential will be screened with a urine BHCG).
  • Patients with stroke activation or symptoms.
  • Patients with trauma activations.
  • Patients over the age of 100 years old are excluded as they make up a small percentage of the population and may become identifiable because of their age.
  • Imaging study does not show evidence of ureteral stone.

Treatment and study plan

Magnesium sulfate

Drug

D5W

Drug

Primary outcomes

  1. Pain Score Change

    Time frame: 1 hour after the completion of treatment medication (Placebo or Study Drug)

    We asked the patient's pain score on a scale of 0-10 with 10 being the highest amount of pain and 0 no pain, before and after treatment (approximately 1 hour). Primary Outcome was the change in score before and after treatment.

Secondary outcomes

  1. Percentage of Participants Requiring Opiates for Additional Pain Control

    Time frame: Any opiate administration required after re-evaluation of pain score after initial treatment with either placebo or study drug

    We analyzed how many patients required additional pain control with opiates between the two treatment groups.

Sponsors and collaborators

Lead sponsor

Henry Ford Health System

Other

Registry information

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Aug 6, 2018
Registry last updated
Mar 24, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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