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Active, Not Recruiting

NCT Number: NCT07710638

Efficacy of Ivermectin in the Treatment of Plane Warts

This study aims to evaluate the efficacy of ivermectin in the treatment of plane warts( flat warts). patients diagnosed with plane warts will be included to assess the clearance ratre of the lesions.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Plane Warts

Age range

5 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Department of Dermatology , Al-Azhar university hospital

Asyut, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

• Clinical and dermoscopic diagnosis of the plane warts.

  • No prior treatment for warts in the last 4 weeks.
  • Patients of both sex (male - female)
  • Age more than 5 years or weight more than 15 kg.

Exclusion criteria

  • • Patients with other types of warts (e.g., common, plantar, genital).
  • History of hypersensitivity or allergy to ivermectin or its components.
  • Patients who have received systemic immunosuppressive therapy within the last 3 months.
  • Presence of chronic skin conditions that may interfere with evaluation (e.g., eczema, psoriasis).
  • Patients with immunodeficiency disorders (e.g., HIV, organ transplant recipients).
  • Pregnant or lactating females.
  • Patients currently on systemic antiviral or immunomodulatory treatment.

Treatment and study plan

Ivermectin

Drug

An antiparasitic medication evaluated for its immunomodulatory and antiviral efficacy in clearing plane warts. it will be administered to patients according to their assigned group protocol.

Placebo

Other

Patients in the control group will receive placebo,they will undergo standard clinical observation and follow up to monitor the natural course of the plane warts.

Primary outcomes

  1. percentage of patients achieving complete clearance of plane warts

    Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

A Prospective Randomized Controlled Clinical Trial to Evaluate the Efficacy of Oral and Topical Ivermectin in the Treatment of Plane Warts

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Jul 17, 2026
Registry last updated
Jul 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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