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Completed

NCT Number: NCT03260829

Efficacy of Injectable Vitamin C on Accelerating Canine Movement: A Clinical Study

efficacy of the injectable vitamin C to reduce the time of canine traction

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Key information

Conditions

Palatally Impacted Canines

Age range

15 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Oral and Dental Medicine

Giza, Giza Governorate, 11311, Egypt

About this study

Objective. The purpose of this study is to investigate the role and efficiency of the locally injected vitamin C in the enhancement of the palatally impacted canine movement.

Design. Twelve adult patients with unilateral palatally impacted canines were included in this study. The enrolled patients were randomly allocated into the study groups; control group; orthodontic traction and he test group: orthodontic traction enhanced by intraepidermic vitamin C injection. The study duration was 12 months.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • medically free
  • patient with good to fair oral hygiene (gingivitis may be included)
  • both sexes were included
  • unilateral palatally positioned permenant canines
  • absence of previous orthodontic treatment
  • absence of supernumerary teeth, odontoms, cysts, traumatic injuries
  • the α angle within grade II to III

Exclusion criteria

  • systemic diseases especially diabetes and bone diseases
  • pregnant and lactating mothers
  • Local causes (smoking, mouth breathing, local trauma and periodontitis).

Treatment and study plan

Vitamin C

Drug

25 IU of vitamin C injected intraepidermally for 6-8 visits till eruption achieved

Other names: ascorbic acid

Primary outcomes

  1. rate of tooth movement

    Time frame: 12 months

    the achieved movement in millimeters in one year

Secondary outcomes

  1. level of alveolar bone

    Time frame: 12 months

    the level of the interproximal and facial alveolar bone after orthodontic treatment with or without injection

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Evaluation of the Effect of Local Injected Vitamin C on Accelerating the Orthodontic Movement of Maxillary Canine Impaction: A Clinical Trial

Acronym: mesotherapy

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Aug 24, 2017
Registry last updated
Aug 29, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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