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OpenTrials
Completed

NCT Number: NCT04686760

Efficacy of Inhaled Nitroglycerin in Moderate to Critically Ill COVID-19 Patients

In current analysis moderate to severely ill Covid-19 infected patients will be nebulized with nitroglycerin, and they will be compared with the standard nebulization

Completed

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bahria Town International Hospital

Lahore, Punjab Province, 54000, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed admitted cases of Covid-19 degree of illness should be moderate to severe both male and female every age group

Exclusion criteria

allergic to nitroglycerin sudden drop in blood pressure not given consent

Treatment and study plan

Nitroglycerin

Drug

2 mg/ml solution of nitroglycerin used for nebulization four hourly

Primary outcomes

  1. ratio of partial pressure of oxygen in arterial blood to fraction of inhaled oxygen

    Time frame: 5-7 days

  2. Oxygen demand

    Time frame: 5-7 days

Secondary outcomes

  1. Duration of hospital stay

    Time frame: 15 days

Sponsors and collaborators

Lead sponsor

University of Lahore

Other

Registry information

Official study title

Efficacy of Inhaled Nitroglycerin in Moderate to Severe Cases of COVID-19 Patients

Important dates

Study start
2020
Primary completion
2021
Study completion
2022
First posted
Dec 29, 2020
Registry last updated
May 18, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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