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Completed

NCT Number: NCT03684577

Efficacy of Hypnotherapy for Agoraphobia

The purpose of the study is to compare the efficacy of Hypnotherapy for the treatment of Agoraphobia compared to a wait-list control group.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Prof. Dr. A. Batra/ Dr. Kristina Fuhr, University Department for Psychiatry and Psychotherapie

Tübingen, 72076, Germany

About this study

With the present study, the efficacy of 8-12 sessions of individual Hypnotherapy will be compared to a wait-list control groups. At study entry and at the end of treatment with Hypnotherapy, the Agoraphobia symptoms will be assessed via clinician-rating and self-report. It is expected that Hypnotherapy will be superior to a wait-list control regarding the percentage reduction of the anxiety symptoms after three months of treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Written informed consent
  • Patient fulfills DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) criteria for agoraphobia
  • 18 - 65 years of age
  • Sufficient knowledge of the German language in order to participate in the study
  • Sufficient availability to participate in weekly therapy sessions

Exclusion criteria

  • Acute suicidality (intended action, concrete plans or intermittent pronounced suicidal ideation)
  • Lifetime diagnosis of a bipolar disorder or psychotic disorder
  • Alcohol or substance use disorder without abstinence in the last 12 months
  • Severe cognitive impairments (in cases of suspicion evaluation via Mini Mental State Test (MMST) < 26, will be conducted)
  • Other severe primary mental disorders to be treated: severe Major Depressive Disorder, severe personality disorder of borderline type with self-injury, severe combined personality disorder, actual posttraumatic stress disorder, anorexia nervosa, obsessive compulsive disorder
  • Somatic disorder impeding participation in regular psychotherapy sessions
  • Outpatient psychotherapy during the last twelve months.
  • Medication with anxiolytics or anti-psychotics (antidepressant medication is permitted if stable since more than eight weeks and no planned changes during the duration of therapy)

Treatment and study plan

Hypnotherapy for Agoraphobia

Behavioral

see description of the experimental arm

Primary outcomes

  1. Panic and Agoraphobia Scale (PAS)

    Time frame: Between baseline (t1) and after 12 weeks (t2)

    The clinician-rating PAS will be used to measure the symptom severity (range 0-56 with higher values indicating more symptoms) for the primary outcome that is defined as the (mean) percentage change of the total symptom score between baseline (t1) and after 12 weeks (t2).

Sponsors and collaborators

Lead sponsor

University Hospital Tuebingen

Other

Registry information

Official study title

Efficacy of Hypnotherapy Compared to a Wait-list Control Group in the Treatment of Agoraphobia

Acronym: WIKI-A

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Sep 25, 2018
Registry last updated
Nov 5, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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