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Completed

NCT Number: NCT06454513

Efficacy of Different Anesthesia Methods in Transbronchial Biopsy

This study investigates the efficacy of different anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy using an electronic bronchoscope. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method, operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status.

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sichuan Provincial People's Hospital

Chengdu, Sichuan, 610072, China

About this study

General anesthesia and local anesthesia are the primary anesthesia methods for interventional respiratory endoscopy. While general anesthesia offers greater comfort, it carries anesthesia-related risks. Local anesthesia, on the other hand, provides a relatively low surgical risk and cost-effectiveness. However, there is limited research on whether its diagnostic value is inferior to that of general anesthesia.This study investigates the efficacy of the two anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy. The study retrospectively analyzed cases of transbronchial biopsy performed at the Respiratory Endoscopy Center of Sichuan Provincial People's Hospital from June 5, 2020, to June 5, 2024. Data collected included age, gender, primary diagnosis, anesthesia method, biopsy method(forcep/cryobiopsy), operation time (excluding general anesthesia and laryngeal mask airway placement time), lesion location and size, pathological results, and follow-up status(pneumothorax、hemorrhage).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Completed Transbronchial Biopsy;the platelets count and PT, APTT tests were normal, normal ECG, Anesthesiologist evaluation was needed in General anesthesia group.

Exclusion criteria

  • patients with contraindication of bronchoscopy (such as respiratory failure and acute cardio-cerebrovascular events), and women who were pregnant.

Treatment and study plan

General Anesthesia

Procedure

Different anesthesia methods

Primary outcomes

  1. Diagnostic efficacy

    Time frame: baseline

    The diagnostic positivity rate(%) of transbronchial biopsy under different anesthesia methods between two groups

Secondary outcomes

  1. Clinical information

    Time frame: baseline

    age(year), gender(male/female), primary diagnosis(lung cancer/pneumonia or other)

  2. lesion location (left/right/other)

    Time frame: baseline

    Clinical information

  3. lesion size (mm)

    Time frame: baseline

    Clinical information

  4. Postoperative complications (hemorrhage or pneumothorax)

    Time frame: baseline

    Clinical information

  5. Operation time

    Time frame: intraoperative

    Clinical information

Sponsors and collaborators

Lead sponsor

Sichuan Provincial People's Hospital

Other

Registry information

Official study title

Exploration on the Efficacy of Different Anesthesia Methods in Transbronchial Biopsy

Acronym: EDAMTBB

Important dates

Study start
2020
Primary completion
2024
Study completion
2024
First posted
Jun 12, 2024
Registry last updated
Jun 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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