Skip to main content
OpenTrials
Completed

NCT Number: NCT03111433

Efficacy of Coenzyme q10 in Pediatrics With Type 1 Diabetes Mellitus

The purpose of this study is to determine wether coenzyme Q10 is effective in reducing markers of endothelial dysfunction in pediatric patients with type 1 diabetes mellitus and aslo to investigate its effect on glycemic control and lipid profile of those patients and its effect on patient's quality of life.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Diabetes Mellitus, Type 1 Autoimmune Diseases Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Immune System Diseases Metabolic Diseases Nutritional and Metabolic Diseases

Age range

8 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Ainshams university pediatric's hospital

Cairo, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age: patients from 8 to 18 years old.
  • Outpatient with at least 1 year history of type 1 diabetes mellitus.
  • Insulin requirement of more than or equal 0.5 U/Kg/day.
  • Approval to participate and give informed consent.

Exclusion criteria

  • Presence of systemic disorders such as celiac disease, hypothyroidism or hyperthyroidism.
  • Preexisting cardiovascular disease or hypertension.
  • Chronic kidney disease or chronic liver disease.
  • Significant mental illness.
  • Intake of other antioxidants such as ascorbic acid and α-tocopherol and omega3 supplement within the last 3 months.
  • Intake of coenzyme Q10 within the last 3 months.

Treatment and study plan

Coenzyme Q10

Dietary Supplement

Coenzyme Q10 soft gelatin capsule 100mg

Insulin

Drug

multiple dose insulin injection therapy

Primary outcomes

  1. change in soluble interacellular adhesion molecule level

    Time frame: three months

    it will be assessed at baseline and after three months of treatment

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Effect of Coenzyme Q10 on Markers of Endothelial Dysfunction in Pediatric Patients With Type 1 Diabetes Mellitus

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Apr 12, 2017
Registry last updated
Apr 3, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.