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Completed

NCT Number: NCT04890223

Efficacy of Brief MI Delivered Via Mobile Instant Messaging to Help Unmotivated Smokers With Chronic Diseases to Quit

This study aims to examine the efficacy of brief MI delivered by mobile instant messaging tools in promoting smoking cessation among unmotivated smokers with chronic diseases. Participants in the intervention group will receive a brief MI intervention while the control group will receive a placebo intervention.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Hong Kong

Hong Kong

About this study

Smoking plays a causal role in the development of chronic diseases and may increase the risk of disease progression or recurrence, elevate the risk of mortality, and reduce the efficacy of treatment for disease sufferers. However, a majority of smokers with chronic diseases are unmotivated, having no intention to quit. These characteristics underscore the critical need for appropriate and effective smoking cessation interventions targeting this population. Nevertheless, most existing smoking cessation services are generic, and none seems to target smokers suffering from chronic diseases. A systematic review indicated that no study had yet examined the efficacy of a smoking cessation intervention designed specifically for unmotivated smokers with chronic diseases. Though MI was effective in promoting smoking cessation among the general population, was not effective for smokers with chronic diseases, who as has been seen tend to be unmotivated smokers. Brief MI, accordingly, is better suited to reaching these smokers in clinical settings, but the application of this approach to smoking cessation contexts has not been well studied.

The proposed intervention will be designed to promote smoking cessation among unmotivated smokers with chronic diseases. To reduce the influence of the participants' baseline characteristics on the efficacy of the intervention, this study will be designed to motivate them to change a selected unfavourable behaviour as a means to reduce their resistance to the intervention. The foot-in-the-door technique served both to facilitate the recruitment for the study and to enhance the participants' compliance with the intervention, in the latter case by promoting change in their selected unfavourable behaviour as a preliminary to further change. The rationale is that a small successful step increases readiness to take a further, larger step, in this case, smoking cessation.

Given that the exponential growth in the number of users of mobile instant messaging tools, they represent a resource for efforts to promote health and enhance treatment compliance. These were among the considerations that informed the development in this study of an intervention using brief MI delivered by mobile instant messaging tools to facilitate smoking cessation among unmotivated smokers with chronic diseases.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hong Kong Chinese over the age of 17
  • Had smoked at least one cigarette per day over the previous three months
  • Had been diagnosed with at least one chronic disease
  • Able to speak Cantonese and read Chinese
  • Willing to take action to improve their health but had no intention to quit smoking
  • Had a smartphone and were able to use mobile instant messaging tools
  • Willing to receive health promotion advice and communicate through mobile instant messaging

Exclusion criteria

  • Participating in other smoking cessation programs or services
  • With mental or cognitive impairment or communication problems

Treatment and study plan

Brief MI intervention

Behavioral

Brief MI intervention

Placebo intervention

Behavioral

Generic health advice consultations and self-help smoking cessation booklets

Primary outcomes

  1. Biochemically validated smoking abstinence at 12 months

    Time frame: 12-month follow-up

    The participants who self-reported not smoking within the past seven days will be invited to submit to a biochemical verification test of smoking abstinence, including an exhaled CO test and a salivary cotinine test. Smoking abstinence is defined as an exhaled CO level of less than 4 ppm and a saliva cotinine level lower than 15 ng/ml.

Secondary outcomes

  1. Biochemically validated smoking abstinence at 6 months

    Time frame: 6-month follow-up

    The participants who self-reported not smoking within the past seven days will be invited to submit to a biochemical verification test of smoking abstinence, including an exhaled CO test and a salivary cotinine test. Smoking abstinence is defined as an exhaled CO level of less than 4 ppm and a saliva cotinine level lower than 15 ng/ml.

  2. Self-reported smoking abstinence

    Time frame: 3-, 6-, or 12-month follow-ups

    Self-reported not smoking within the past seven days

  3. Intention to quit

    Time frame: 3-, 6-, or 12-month follow-ups

    Individual's readiness to quit smoking within six months

  4. Self-reported smoking reduction of at least 50%

    Time frame: 3-, 6-, or 12-month follow-ups

    Reduction in cigarette consumption from the baseline by at least 50%

  5. Quit attempts

    Time frame: 3-, 6-, or 12-month follow-ups

    A period of intentional abstinence of more than 24 hours

  6. Self-reported behavioural change

    Time frame: 3-, 6-, or 12-month follow-ups

    Individual's perceived modification of the selected unfavourable behaviour

Sponsors and collaborators

Lead sponsor

The University of Hong Kong

Other

Registry information

Official study title

Efficacy of Brief Motivational Interviewing Delivered Via Mobile Instant Messaging Tools to Promote Smoking Cessation Among Unmotivated Smokers With Chronic Diseases

Important dates

Study start
2021
Primary completion
2023
Study completion
2023
First posted
May 18, 2021
Registry last updated
Aug 7, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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