Skip to main content
OpenTrials
Completed

NCT Number: NCT02528773

Efficacy of ART to Interrupt HIV Transmission Networks

The investigators are conducting a study to learn more about the spread of HIV infection within different geographic regions and populations in San Diego County, with the goal of demonstrating that early use of HIV treatment can reduce the number of new infections in our community. At the study visits, participants will be examined by the study staff and asked to donate some blood. Participants will also be asked several questions about themselves, their background, behaviors, health, and the general geographic area in which they live. By collecting information about antiretroviral treatment choices that are made by study participants, the investigators will be better able to measure how effectively HIV treatment can interrupt (i.e., block) the spread of HIV. All of the information gathered at the study visits will be de-identified and analyzed. Study staff will use the information to better understand in which groups of people, and in what areas of San Diego, HIV is spreading most quickly. This information will be used to determine how well Antiretroviral Therapy (HIV treatment) by certain individuals can control the spread of HIV within the population.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

HIV

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

UCSD AntiViral Research Center

San Diego, California, 92103, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years of age
  • Newly diagnosed HIV infection
  • ART naïve (≤7 days ART, previous use of PEP or PrEP are not exclusions)
  • Subject must be able to provide written consent
  • Subject must agree to study specific specimen collections and visit schedule.
  • Subjects with newly diagnosed HIV infection who were identified on or after May 1, 2014 will be eligible for enrollment as long as they are co-enrolled to either AEH020 (project 08-0278) or AEH030 (project 140093) and DID meet the above study inclusion criteria (items at the time of enrollment to protocols AEH020 or AEH030).

Exclusion criteria

  • Any factor or factors that in the opinion of the local investigator that could prevent compliance with study requirements.
  • Contraindication to phlebotomy or specimen collection.

Treatment and study plan

Primary outcomes

  1. Network-level efficacy of ART as measured by the number of newly infected persons and network cluster growth over time

    Time frame: 5 Years

Sponsors and collaborators

Lead sponsor

University of California, San Diego

Other

Registry information

Acronym: ART-NET

Important dates

Study start
2014
Primary completion
2020
Study completion
2020
First posted
Aug 19, 2015
Registry last updated
Nov 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.