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Completed

NCT Number: NCT01192802

Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora

Albendazole is a main anti-helminth, however there is a lack of data regarding its efficacy in the school children population. The aim of this study is to evaluate the efficacy of the albendazole one versus two and three doses, in school children infected with intestinal helminth.

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Key information

Conditions

Intestinal Diseases Digestive System Diseases Gastrointestinal Diseases Helminthiasis Hookworm Infections Infections Nematode Infections Parasitic Diseases Secernentea Infections Strongylida Infections

Age range

4 year–14 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Medical research Unit of Lambaréné

Lambaréné, Moyen-Ogooué Province, 118, Gabon

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • presence of intestinal helminths eggs in the stool

Exclusion criteria

  • allergy to imidazole derivate
  • No intestinal helminths

Treatment and study plan

Albendazole

Drug

1 tablet of 400 mg of albendazole per day for three consecutive days

Primary outcomes

  1. parasite cleared and reduced up to 80% at day 42

    Time frame: 42 days

Secondary outcomes

  1. Prevalence of major gut bacteria

    Time frame: 42 days

    Change in the prevalence of major gut bacteria after antihelminth treatment.

Sponsors and collaborators

Lead sponsor

Albert Schweitzer Hospital

Other

Registry information

Official study title

Effect of Intestinal Helminths on Gut Microflora

Important dates

Study start
2010
Primary completion
2012
Study completion
2012
First posted
Sep 1, 2010
Registry last updated
Jan 24, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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