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OpenTrials
Completed

NCT Number: NCT04225091

Efficacy Evaluation of Triple up® Collagen Drink on Skin Condition

To assess Triple up® Collagen Drink on skin condition improvement

Completed

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Key information

Conditions

Skin Condition Skin Diseases Skin and Connective Tissue Diseases

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chia Nan University of Pharmacy ＆ Science

Tainan, 71710, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults aged above 20 years old

Exclusion criteria

  • Subject who is not willing to participate in this study.
  • Patients with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history).
  • Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
  • Female who is pregnant or nursing or planning to become pregnant during the course of the study.
  • Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
  • Vegetarian
  • Subjects who have large spots (area >3 square centimeter) or abnormal acne.

Treatment and study plan

Testing product

Dietary Supplement

consume 1 bottle (50 mL) per day for 28 days

Other names: Triple up® Collagen Drink

Blank

Dietary Supplement

consume 1 bottle (50 mL) per day for 28 days

Other names: Placebo drink

Primary outcomes

  1. The change of skin moisture

    Time frame: Change from Baseline skin moisture at 4 weeks

    Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120

  2. The change of skin elasticity

    Time frame: Change from Baseline skin elasticity at 4 weeks

    Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves

  3. The change of skin wrinkles

    Time frame: Change from Baseline skin wrinkles at 4 weeks

    VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units

  4. The change of skin collagen density

    Time frame: Change from Baseline skin collagen density at 4 weeks

    DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units: Intensity score

Secondary outcomes

  1. The change of skin texture

    Time frame: Change from Baseline skin texture at 4 weeks

    VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

  2. The change of skin pores

    Time frame: Change from Baseline skin pores at 4 weeks

    VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units

Sponsors and collaborators

Lead sponsor

TCI Co., Ltd.

Industry

Registry information

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Jan 13, 2020
Registry last updated
Nov 30, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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