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Completed

NCT Number: NCT03350893

Efficacy Evaluation of the Probiotics Containing Skincare Products on Skin

Previous studies on skin health with Lactic acid bacteria (LAB) have been published for many years, including prevention of skin diseases and improvement of skin conditions. In this clinical study, the investigators researched the benefit effects of heat-killed Lactobacillus plantarum cream on skin health.

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Key information

Conditions

Skin Problems

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chia Nan University of Pharmacy and Science

Tainan, 71710, Taiwan

About this study

To evaluate the efficacy of applying probiotic cream in the ameliorationof the whole face skin conditions such as moisturizing, whitening, anti-wrinkle and so on.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy volunteers between the ages of 20-60.

Exclusion criteria

  • Subjects with photosensitivity (Sun allergy).
  • Subjects are undergoing medical therapy for skin diseases.
  • Subjects with severe hyperpigmentation.
  • Subjects with diabetes.
  • Subjects with cosmetics allergy.
  • Subjects who have recently participated laser therapies or other treatments are not suitable for sun.

Treatment and study plan

Emulsion base with probiotics

Combination Product

Water、Polyglyceryl-3/ Methylglucose Distearate、Triethyl Hexanoin、Macadamia Ternifolia Seed Oil、Propanediol、PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin、Cetyl Alcohol、Myristyl Myristate、Glycerin、Glycosyl Trehalose/Hydrogenated Starch Hydrolysate、Rice Ferment Filtrate(Sake)、Saccharomyces/Daylily Flower Ferment Filtrate、Bis-PEG/PPG-20/5 PEG/PPG-20/5Dimethicone、Methoxy PEG/PPG-25/4 Dimethicone、Caprylic/Capric Triglyceride、Sodium Polyacrylate、Phenoxyethanol、o-Cymen-5-ol、Xanthan Gum、Potassium Hydroxide, Heat-killed L. plantarum powders (1x10^9 cells/ g-cream)

Other names: Active Group

Emulsion base

Other

Water、Polyglyceryl-3/ Methylglucose Distearate、Triethyl Hexanoin、Macadamia Ternifolia Seed Oil、Propanediol、PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin、Cetyl Alcohol、Myristyl Myristate、Glycerin、Glycosyl Trehalose/Hydrogenated Starch Hydrolysate、Rice Ferment Filtrate(Sake)、Saccharomyces/Daylily Flower Ferment Filtrate、Bis-PEG/PPG-20/5 PEG/PPG-20/5Dimethicone、Methoxy PEG/PPG-25/4 Dimethicone、Caprylic/Capric Triglyceride、Sodium Polyacrylate、Phenoxyethanol、o-Cymen-5-ol、Xanthan Gum、Potassium Hydroxide

Other names: Control Group

Primary outcomes

  1. Skin Diagnosis

    Time frame: Baseline, 4 weeks and 8 weeks

    The changes of skin condition by VISIA Complexion Analysis System

Secondary outcomes

  1. Skin Moisture

    Time frame: Baseline, 4 weeks and 8 weeks

    The changes of skin moisture by Skicon-200EX and Corneometer CM 825

  2. Skin Color

    Time frame: Baseline, 4 weeks and 8 weeks

    The changes of skin color by DermaSpectrometer

Sponsors and collaborators

Lead sponsor

GenMont Biotech Incorporation

Industry

Collaborators

  • Chia Nan University of Pharmacy and Science

Registry information

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Nov 22, 2017
Registry last updated
Aug 16, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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