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OpenTrials
Completed

NCT Number: NCT06194487

Efficacy Evaluation of Collagen Drink Products

To assess MAXI Collagen drink on skin condition improvement

Completed

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Key information

Conditions

Skin Condition Skin Diseases Skin and Connective Tissue Diseases

Age range

35 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Applied Cosmetology, Hungkuang University

Taichung, 433304, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults aged 35-65 years old

Exclusion criteria

  • Subject with skin surface damage larger than $50 coin area.
  • Subject who had skin allergies caused by diet or undrwent cosmetic or medical treatment within 6 months.
  • Subject who is a vegetarian and allergic to seafood, alcohol or listed ingredients in the product.
  • Students who are currently taking courses taught by the principal investigator of this trial.

Treatment and study plan

Placebo drink

Dietary Supplement

consume 1 bottle (50mL) per day

MAXI Collagen Drink

Dietary Supplement

consume 1 bottle (50mL) per day

Normal fish collagen drink

Dietary Supplement

consume 1 bottle (50mL) per day

Primary outcomes

  1. The change of skin collagen density

    Time frame: Day 0, Day 7, Day 28

    DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units

  2. The change of skin elasticity

    Time frame: Day 0, Day 7, Day 28

    Cutometer® Dual MPA 580 was utilized to measure skin elasticity. Units: arbitrary units

  3. The change of skin moisture

    Time frame: Day 0, Day 7, Day 28

    Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120

  4. The change of skin texture

    Time frame: Day 0, Day 7, Day 28

    VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

Secondary outcomes

  1. The change of transepidermal water loss (TEWL)

    Time frame: Day 0, Day 7, Day 28

    Tewameter® TM 300 was utilized to measure TEWL. Units: g/hm²

  2. The change of skin wrinkles

    Time frame: Day 0, Day 7, Day 28

    VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

  3. The change of skin pores

    Time frame: Day 0, Day 7, Day 28

    VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units

  4. The change of skin colour

    Time frame: Day 0, Day 7, Day 28

    PANTONE® CAPSURE™ RM200-PT01 was utilized to measure skin colour. Units: arbitrary units

  5. The change of self-assessment skin condition

    Time frame: Day 0, Day 7, Day 28

    A self-assessment questionnaire was collected to evaluate skin condition

Other outcomes

  1. The change of liver function biomarkers (GOT, GPT) of blood

    Time frame: Day 0, Day 28

    Fasting venous blood was sampled to measure liver function biomarkers

  2. The change of renal function biomarkers (creatinine, BUN) of blood

    Time frame: Day 0, Day 28

    Fasting venous blood was sampled to measure renal function biomarkers

  3. The change of fasting blood glucose

    Time frame: Day 0, Day 28

    Fasting venous blood was sampled to measure blood glucose

Sponsors and collaborators

Lead sponsor

TCI Co., Ltd.

Industry

Registry information

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
Jan 8, 2024
Registry last updated
May 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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