Skip to main content
OpenTrials
Completed

NCT Number: NCT00492076

Efficacy and Safety Trial of Subcutaneous Immunotherapy in Mite Induced Asthma

The purpose of this study is to determine whether a short course of subcutaneous immunotherapy is efficacious in mite induced asthma. The efficacy is based on reduction in control medication.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Allergic Asthma Asthma Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

14 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Hospital Virgen del Camino, Allergology Service

Pamplona, Navarre, 31002, Spain

About this study

The control of mild-moderate persistent asthma include the need of concomitant medication, as inhaled corticosteroids. However, compliance in perennial asthma is low. The aim of this study is to assess the possibility to reduce the need of concomitant medication through a short-course of subcutaneous immunotherapy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Mild/moderate persistent asthma
  • Positive skin prick test or specific IgE to mites
  • Age: 14-55 years old

Exclusion criteria

  • Immunotherapy contraindications
  • Allergy to other inhalant allergens
  • Previous immunotherapy (5 years)with mites

Treatment and study plan

Pangramin Plus D. pteronyssinus 100%

Biological
  • Active. Pangramin Plus D. pteronyssinus 100%
  • Placebo. Pangramin Plus placebo

Primary outcomes

  1. Reduction in inhaled corticosteroids

    Time frame: 4 months

Secondary outcomes

  1. Reduction in symptoms and rescue medication Tolerability

    Time frame: 4 months

Sponsors and collaborators

Lead sponsor

ALK-Abelló A/S

Industry

Registry information

Official study title

A Randomised, Double-Blind Placebo-Controlled Study Assessing the Short-Term Effect of a Dermatophagoides Pteronyssinus Extract, Quantified in Mass Units, in Subjects With Perennial Mite Induced Asthma

Important dates

Study start
2006
Primary completion
2008
Study completion
2008
First posted
Jun 27, 2007
Registry last updated
Oct 16, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.