Efficacy and Safety Study of Total Glucosides of Paeony Combined With Acitretin to Treat Psoriasis

Inclusion criteria

Meet the following conditions

• Diagnosed according to Classification criteria for Psoriasis vulgaris;
• Patients aged 18 to 65 years (to the date of screening);
• PASI grade>7point<20 point;
• Not treatment in the Topical corticosteroids、Immunosuppresso、Biologicals agents or Tretinoin cream、Phototherapy nearly one months before enrolled.
• Understanding the whole process of the study, voluntary participation and signed the informed consent;
• Patient compliance is good, can guarantee in course of observation.

Exclusion criteria

One of the following is not included in this study:

• Pregnant women, ready to pregnant or lactating women;
• Known to root of herbaceous peony total glycosides (TGP) drug allergy;
• Have a serious heart, lung, kidney and other vital organs and endocrine system lesions and the history
• Patients is liver function abnormal persons (ALT above the center laboratory normal limit) or hepatitis b patient grain carriers;
• Need insulin control of diabetes; High blood pressure did not get good controller ;
• Patients with white blood cells <4.0 × 109 / L, or a definite anemia (hemoglobin less than 100g / L), or platelets <100 × 109 / L, or other blood disease;
• Patients with chronic diarrhea, or peptic ulcer nearly 1 year;
• Patients suffering from malignant tumor;
• Patients suffering from acute and chronic infectious diseases;
• Mental disorders, history of alcohol abuse, drug or other substance abuse; 11. Other cases which researchers believe that can not enroll.