Skip to main content
OpenTrials
Completed

NCT Number: NCT06849674

Efficacy and Safety of Platelet-Rich Plasma as an Intraoperative Holding Solution in Hair Transplantation

The goal of this study is to determine the efficacy of using platelet-rich plasma (PRP) versus 0.9% normal saline as a storage solution during follicular unit extraction (FUE) hair transplantation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hair Transplantation

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Dermatology, Venereology and Andrology Faculty of Medicine- Benha University

Banhā, Qalyubia Governorate, 13511, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male patients who have androgenetic alopecia
  • Patients who are interested in having their hair transplanted

Exclusion criteria

  • Individuals with comorbidities
  • History of keloids or hypertrophic scarring
  • Low donor area density
  • Other causes of alopecia
  • Scalp infections
  • Patients with a bleeding tendency
  • Patients on anticoagulant therapy
  • Patients who are HIV-positive or Hepatitis B- or C-positive

Treatment and study plan

Platelet Rich Plasma (PRP)

Biological

Hair grafts will be immersed in autologous Platelwt-richh plasma(PRP) before transplantation.

Saline

Other

Hair grafts will be immersed in normal saline solution before transplantation.

Primary outcomes

  1. Change in Hair density

    Time frame: 12 weeks after hair transplantation

    Hair density (the number of hairs per square centimeter) will be measured using a trichoscope and digital photography in the recipient area.

  2. Percentage of Hair Growth

    Time frame: 12 weeks after hair transplantation

    The percentage of graft survival will be assessed by comparing the number of transplanted hairs to the number of hairs that have grown in the recipient area using trichoscopic analysis and digital photography. The formula used will be: (number of grown hairs/number of transplanted hairs) x100%

Secondary outcomes

  1. Patient satisfaction score

    Time frame: 12weeks after hair translantation

    Patient satisfaction will be assessed using Likert scale from 1 to 5 regarding aesthetic results, hair density, and natural appearance. Higher scores indicate greater satisfaction.

  2. Incidence of Postoperative complications

    Time frame: within 1 month after hair transplantation

    The number and type of complications, including infection,graft necrosis, excessive shedding, and scalp irritation, will be documented. The severity of complications will be assessed using clinical examination and patient reports

Sponsors and collaborators

Lead sponsor

Benha University

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Feb 27, 2025
Registry last updated
Feb 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.