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OpenTrials
Completed

NCT Number: NCT00202579

Efficacy and Safety of Ivabradine in Severe Congestive Heart Failure

To evaluate the effects on heart function of ivabradine administered to patients with severe chronic heart failure

Completed

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Key information

Conditions

Heart Failure, Congestive Cardiovascular Diseases Heart Diseases Heart Failure

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Policlinico San Matteo

Pavia, 27100, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • systolic congestive heart failure
  • sinus rhythm, HR >= 80bpm

Exclusion criteria

  • unstable cardiovascular condition

Treatment and study plan

Ivabradine

Drug

Primary outcomes

  1. Haemodynamic parameters

  2. Twelve-lead ECG

  3. Systolic and diastolic blood pressure

Secondary outcomes

  1. Echocardiography

  2. Neurohormones

Sponsors and collaborators

Lead sponsor

Institut de Recherches Internationales Servier

Other

Registry information

Official study title

Evaluation of the Effects on Peripheral and Central Haemodynamics Parameters, Safety, and Tolerance of Three-hour Intravenous Perfusion (0.1 mg/kg) of Ivabradine Given to Severe Congestive Heart Failure Patients

Important dates

Study start
2004
Study completion
2006
First posted
Sep 20, 2005
Registry last updated
Jul 25, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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