Efficacy and Safety of Colorectal Anastomotic Leak Testing

Inclusion criteria

• Patients diagnosed with colorectal cancer by pathology and scheduled for surgical treatment who meet the surgical indications.
• Aged between 18 and 85 years.
• American Society of Anesthesiologists (ASA) physical status classification is I - III.
• The patient or his/her legal representative can understand and sign the informed consent form and is willing to cooperate throughout the study process.

Exclusion criteria

• Patients with preoperatively diagnosed anastomotic leak or other severe abdominal infections.
• Patients with severe cardiovascular and cerebrovascular diseases (such as recent myocardial infarction, unstable angina pectoris, severe heart failure, acute cerebral infarction, etc.) who cannot tolerate surgery and related tests.
• Patients with severely impaired liver and kidney function (liver function Child - Pugh classification C or above, creatinine clearance rate < 30 ml/min).
• Patients with coagulation disorders (such as platelet count < 50×10⁹/L, international normalized ratio (INR) > 1.5, etc.) that cannot be corrected or are receiving anticoagulant therapy that cannot be adjusted.
• Patients with a history of abdominal radiotherapy or multiple abdominal surgeries and severe abdominal adhesions that may affect the operation and detection procedures.
• Patients with other malignant tumors who are receiving active anti-tumor treatment such as radiotherapy and chemotherapy.
• Patients with mental illness or cognitive impairment who cannot cooperate with the study process and follow-up.