Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis.

Inclusion criteria

• Adults, ≥ 40 years
• Pain located at the root of the thumb (near the wrist) and awakened by direct pressure and movement
• Pain resistant to well-conducted medical treatment, with analgesics, NSAIDs, icing with pain (analog visual scale) ≥ 4 for more than 3 months
• Radiological findings (kapandji face + profile incidence) typical of rhizarthrosis, stage II or III of Eaton and Litter, with at least 2 of the following 5 radiological elements observed on the trapeziometacarpal joint:

• marginal osteophyte
• pinching of the joint space
• sclerosis of the subchondral space
• subchondral kyst
• absence of osteopenia
• Patient with the ability to understand the protocol and signed informed consent
• Patient receiving social security

Exclusion criteria

• Known allergy to any of the products (corticosteroids or hyaluronic acid) including its excipients (methyl parahydroxybenzoate, propyl parahydroxybenzoate, benzyl alcohol)
• Change of analgesic treatment within 4 weeks before inclusion.
• Patients with symptomatic bilateral rhizarthrosis
• Scaphoid-trapezial arthrosis
• Local or general infection
• Severe coagulation disorders, ongoing anticoagulant therapy
• severe and / or uncontrolled hypertension
• Earlier local surgery
• Associated inflammatory rheumatism
• Tendinopathy of De Quervain, thumb to jump associated
• Infiltrations earlier than 6 months
• Diabetes imbalanced
• Live vaccines
• Severe water and / or sodium retention (hypernatremia), particularly in cases of heart failure, decompensated liver failure (edema and ascites failure)
• Pregnant or lactating women
• Immunocompromised or hemodialysis patients
• Patients under guardianship, trusteeship, or deprived of liberty
• Patients participating in another clinical research protocol involving a drug or medical device
• Patients unable to follow the protocol, according to the judgment of the investigator