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OpenTrials
Completed

NCT Number: NCT03650322

Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors

The investigators propose to compare the effects of a 12-week, supervised, site-based group yoga intervention on cognitive function, functional fitness, and well-being in middle-aged cancer survivors. Subjects will be randomly assigned to one of three exercise conditions: a yoga group, an aerobic walking group or a strength training group. All sessions (2-3 times per week) will be led by a trained exercise leader for a total of 150 minutes of exercise each week for the 12-week intervention.

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Key information

Conditions

Cancer Behavior Cancer-related Problem/Condition Exercise Motor Activity Neoplasms

Age range

30 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Illinois at Urbana-Champaign

Urbana, Illinois, 61801, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 30-70 years of age
  • Cancer diagnosis
  • 1 year since last cancer treatment (surgery, chemotherapy, and/or radiation)
  • Not planning to receive treatment during study period
  • Completion of Physical Activity Readiness Questionnaire (PAR-Q)
  • Ambulatory and absence of health conditions that may be exacerbated by yoga, walking, or strength training
  • Physician consent (if deemed necessary)
  • Low-active, i.e. less than 150 minutes/week of moderate to vigorous exercise, no current yoga practice (including within last six months)
  • Intention to remain in the Champaign-Urbana area over the study duration
  • Willingness to be randomly assigned to one of the three groups (yoga, aerobic walking, strength training)
  • Comfortable with reading, writing, and speaking English

Exclusion criteria

  • Below 30 or above 70 years of age
  • Cancer diagnosis of the brain
  • Less than 1 year since last treatment (surgery, chemotherapy, and/or radiation) or plans to receive treatment during study
  • Determined ambulatory or 'high risk' based on responses to PAR-Q
  • High-active (exercising more than 150 minutes/week in the last six months)
  • No consent from physician
  • Intent to be away from the Champaign-Urbana area for an extended period of time during the study
  • Inability to communicate effectively in English

Treatment and study plan

Yoga

Behavioral

12 weeks, total of 150 minutes of exercise per week.

Stretching and Toning

Behavioral

12 weeks, total of 150 minutes of exercise per week.

Aerobic Walking

Behavioral

12 weeks, total of 150 minutes of exercise per week.

Primary outcomes

  1. Cognitive Function

    Time frame: Change from baseline to 12 weeks will be reported

    Participants will complete part of the NIH Toolbox measures that assess cognitive function.

Secondary outcomes

  1. Cardiovascular Function

    Time frame: Change from baseline to 12 weeks will be reported

    Participants will complete a submaximal exercise test to reach a target heart rate within 85% of the age-predicted maximum.

Other outcomes

  1. Feasibility: Recruitment and retention rates

    Time frame: Baseline to 12-weeks

    Proportion of participants randomized relative to total contacts, Proportion of participants who complete follow-up questionnaires,

Sponsors and collaborators

Lead sponsor

University of Illinois at Urbana-Champaign

Other

Registry information

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Aug 28, 2018
Registry last updated
Jul 5, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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