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Completed

NCT Number: NCT01316198

Effects of Xanthophylls on Optical Density

The objective of the study was to investigate the influence of a intervention with lutein und zeaxanthin from crucifers on the optical density of the macular pigment of patients with non exudative age-related maculopathy. It is hypothesized that the applied study beverage elevates plasma concentrations of the administered xanthophylls and the optical density after 4 weeks of intervention.

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Key information

Conditions

Age-Related Macular Degeneration Eye Diseases Macular Degeneration Retinal Degeneration Retinal Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Friedrich Schiller University

Jena, Thuringia, 07743, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with non exudative age-related maculopathy

Exclusion criteria

  • intake of dietary supplements containing lutein and zeaxanthin

Treatment and study plan

Verum

Dietary Supplement

10 subjects consume for 4 weeks a beverage containing 10 mg lutein and 3 mg zeaxanthin per day

Placebo

Dietary Supplement

10 subjects consume for 4 weeks a placebo beverage without any lutein and zeaxanthin

Primary outcomes

  1. Optical density of macular pigment in AMD patients

    Time frame: 10 weeks

Secondary outcomes

  1. Concentration of xanthophylls in plasma of AMD patients

    Time frame: 10 weeks

  2. blood lipids

    Time frame: 10 weeks

Sponsors and collaborators

Lead sponsor

University of Jena

Other

Registry information

Official study title

Alteration of Optical Density and Plasma Xanthophylls After Short Term Supplementation With Macular Carotenoids in Patients With AMD

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
Mar 16, 2011
Registry last updated
Jul 27, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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