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Completed

NCT Number: NCT03680027

Effects Of Walnut-Enriched Diet On Blood Lipids And Glucose Profiles In Hyperlipidemic Subjects

Walnuts have been shown to reduce serum lipids in hyperlipidemic individuals with a well-controlled feeding trials. Current study have been determined the effects of daily walnut consumption on serum lipids, fasting glucose and insulin levels in hyperlipidemic individuals.

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Key information

Conditions

Hyperlipidemias Dyslipidemias Lipid Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

30 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

In this, randomized controlled trial, mild to moderate hyperlipidemic subjects were randomly divided into 2 groups as walnut-enriched (n=20) and control (n=17) groups for 6 weeks. All subjects adhered to a medical nutrition therapy as low-fat and low-cholesterol diet. The walnut-enriched group was supplemented with 40 g/day of walnuts added to their diets. In order to follow nutritional status of subjects, they were visited every 15 days (in total 4 times). Anthropometric measurements of the subjects were taken and were monitored at each visit during the study. Blood samples were measured at the beginning and again at the end of the study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hyperlipidemic patients who are not using any lipid lowering medications
  • Non-smoker
  • No alcohol consumption
  • Individuals who are having ≤30kg/m2
  • Individuals who do not have any allergy for nut consumption
  • Female participants who are not pregnant or breastfeeding
  • Individuals should not be in a weight loss programme
  • Having not consumed regular nuts for the last 1 month,
  • Except hypertension, they should not have other chronic diseases (such as diabetes, chronic renal failure)
  • No intense exercise

Exclusion criteria

  • Failure to meet the criteria for inclusion criteria.

Treatment and study plan

Walnut-enriched Group

Dietary Supplement

All subjects supplemented with 40 g/day of walnuts for 6 weeks.

Primary outcomes

  1. Reduction in serum lipids and fasting glucose levels

    Time frame: Six weeks

    In both group, participants have decreased serum total cholesterol and LDL-cholesterol.However especially walnut-enrcihed group significantly changed fasting glucose and insulin levels.

Sponsors and collaborators

Lead sponsor

Eastern Mediterranean University

Other

Registry information

Official study title

Effects Of Walnut-Enriched Diet On Blood Lipids And Glucose Profiles In Hyperlipidemic Subjects: A Randomized-Controlled Trial: A Randomized-Controlled Trial

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Sep 21, 2018
Registry last updated
Sep 24, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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