Facultad de Odontología, Universidad de Antioquia
Medellín, Antioquia, Colombia
NCT Number: NCT01578603
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
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Notify Me16 year–34 year
All sexes
Interventional
Phase 4
Medellín, Antioquia, Colombia
The purpose of this paper is to compare the effect of daily consumption of two sugar-free chewing gum, one with Recaldent and one with Xylitol, added to traditional hygiene (brushing, fluoridated toothpaste and dental floss), in clinical features such as the accumulation of plaque and gingival inflammation, microbiological characteristics of saliva as the counts of cariogenic microorganisms and facultative anaerobes, and some physicochemical properties of saliva such as pH and concentrations of calcium and inorganic phosphate.
To this there was a general call among dental students at the University of Antioquia and those who expressed their intention to participate voluntarily with informed consent, were examined clinically and randomly assigned to one of the study groups (Recaldent or Xylitol) or the control group.
After a month of baseline examination and the daily use of the same instruments of oral hygiene and chewing of 6 pellets of each chewing gum (in the case of study groups), all variables are re-examined.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
6 g/day, for a month, by chewing 2g three times daily after meals.
Other names: sugar alcohol
two pieces of the commercial presentation three times daily after meals
Other names: CPP-ACP complex
Time frame: a month
dental plaque assessment
Time frame: a month
gingival inflammation
Time frame: a month
Time frame: a month
number of Streptococcus mutans in saliva
Time frame: a month
levels of calcium in saliva
Time frame: a month
number of facultative microorganisms in saliva
Time frame: a month
levels of Lactobacillus spp. in saliva
Time frame: a month
inorganic phosphate leves in saliva
Time frame: a month
bleeding on probing
Universidad de Antioquia
Other
Effects of Two Sugar Substituted Chewing Gums Plus Tooth Brushing on Different Caries and Gingivitis Related Variables: a Double Blind, Randomized Controlled Clinical Trial
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