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NCT Number: NCT06112236

Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia

The aim of this study is to generate evidence regarding hypophosphatemia after iron infusion in lung transplant recipients in context of anemia and/or iron deficiency.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Hypophosphatemia Metabolic Diseases Nutritional and Metabolic Diseases Phosphorus Metabolism Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Zurich

Zurich, 8091, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • lung transplant recipient
  • treated at the University Hospital Zurich between 2015 until 2022

Exclusion criteria

  • Denied general consent

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

  1. Change of serum phosphate level

    Time frame: Baseline and up to 90 days after iron infusion

    Change of serum phosphate level before and after iron infusion

Secondary outcomes

  1. Change of urin phosphate level

    Time frame: Baseline and up to 90 days after iron infusion

    Change of urin phosphate level before and after iron infusion

  2. Change of hemoglobin

    Time frame: Baseline and up to 90 days after iron infusion

    Change of hemoglobin level before and after iron infusion

  3. Change of mean corpuscular volume (MCV)

    Time frame: Baseline and up to 90 days after iron infusion

    Changes of serum MCV level before and after iron infusion

  4. Change of mean corpuscular hemoglobin (MCH)

    Time frame: Baseline and up to 90 days after iron infusion

    Change of serum MCH level before and after iron infusion

  5. Change of serum magnesium

    Time frame: Baseline and up to 90 days after iron infusion

    Change of serum magnesium level before and after iron infusion

  6. Change of serum and urin calcium

    Time frame: Baseline and up to 90 days after iron infusion

    Change of serum and urin calcium level before and after iron infusion

  7. Change of serum albumin

    Time frame: Baseline and up to 90 days after iron infusion

    Change of serum albumin level before and after iron infusion

  8. Complications after iron infusion

    Time frame: 2015-2022

    Number of patients with complications due to hypophosphatemia after iron infusion (Hospitalization, hypoxia, fracture due to hypophosphatemia)

  9. Predictors

    Time frame: baseline and up to 90 days after iron infusion

    Analysis of possible predictors for the decrease of serum phosphate levels after iron infusion

  10. Therapeutic management

    Time frame: 2015 to 2022

    Descriptive analysis of therapeutic management of hypophosphatemia after iron infusion

Sponsors and collaborators

Lead sponsor

University of Zurich

Other

Registry information

Important dates

Study start
2023
Primary completion
2026
Study completion
2027
First posted
Nov 1, 2023
Registry last updated
Nov 1, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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