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Completed

NCT Number: NCT03120169

Effects of Treadmill Versus Cycling Endurance Training in Patients With COPD

Aim of this study is to investigate the effects of treadmill versus cycling endurance training on Balance, gait performance and exercise capacity in patients with severe chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized into one of two intervention groups. Walking intensity in the treadmill group will be set at 80 percent of the average speed of the 6-minute walking test. The cycling group will exercise at an intensity of 60 percent according to an Initial incremental cycling test.

Patients will perform 5 to 6 training sessions per week. The total exercise duration will be progressively increased from 10 to 30 minutes. Walking or cycling intensity will also be progressively increased if perceived exertion during exercise is rated below 3 on the modified 10-point Borg scale.

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Key information

Conditions

Chronic Obstructive Pulmonary Disease Behavior Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Motor Activity Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Schoen Klinik Berchtesgadener Land

Schönau am Königssee, 83471, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • COPD Stage III or IV according to the global initiative for chronic obstructive lung disease
  • impaired exercise capacity (6 Minute walk distance of less than 70% of the reference values from Troosters et al.)

Exclusion criteria

  • acute, severe exacerbation of COPD
  • carbon dioxide of more than 45 mmHg at rest
  • any disabilities that prevent patient form walking or cycling
  • Patient is not able to walk 20 meters without any aid (for example rollator)

Treatment and study plan

treadmill endurance training

Other

n = 15 patients with COPD. Walking intensity will be initially set at 80 percent of 6-minute Walking test Speed with progressive increase in Duration and intensity.

cycling endurance training

Other

n=15 patients with COPD. Cycling intensity will initially be set at 60 percent of Peak work rate with progressive increase in Duration and intensity

Primary outcomes

  1. Change in step symmetry during 20m walking

    Time frame: measurement on day 1 and 21

    Patients walk 20m while wearing the Mc Roberts move test device (triaxial accelerometer) which performs a gait analysis

Secondary outcomes

  1. Change in balance performance during semi-tandem stance

    Time frame: measurement on day 1 and 21

    patients stand still for 10 seconds on a force platform that measures absolute path length of the center of force.

  2. Change in balance performance during Romberg stance

    Time frame: measurement on day 1 and 21

    patients stand still for 10 seconds on a force platform that measures absolute path length of the center of force.

  3. Change in balance performance during single leg stance

    Time frame: measurement on day 1 and 21

    patients stand still for 10 seconds on a force platform that measures absolute path length of the center of force.

  4. Change in muscle power during counter movement jump

    Time frame: measurement on day 1 and 21

    patients jump on a force platform as high as possible. The Outcome is Watt per Kilogram Body weight

  5. Change in 1 Minute sit to stand test

    Time frame: measurement on day 1 and 21

    Patients try to perform as many repetitions as possible of standing up and sitting down from a chair with crossed arms on a force platform during 1 minute

  6. Change in 5 Repetition sit to stand test

    Time frame: measurement on day 1 and 21

    Patients try to perform 5 repetitions of standing up and sitting down from a chair with crossed arms on a force platform as quick as possible

  7. Change in peak muscle strength

    Time frame: measurement on day 1 and 21

    isometric peak torque of the knee extensor muscles are measured in 90° knee angle

  8. Change in 4 meter gait Speed test

    Time frame: measurement on day 1 and 21

    patients have to walk 4 meters at their usual Speed. Outcome is the average Speed during the 4m walk.

  9. Change in 6-minute Walk test

    Time frame: measurement on day 1 and 21

    the best out of two 6- Minute Walk Tests will be used for analysis

  10. Change in Hospital anxiety and Depression scale

    Time frame: measurement on day 1 and 21

    the Hospital anxiety and Depression scale is a questionnaire that evaluates signs of anxiety or depression

Sponsors and collaborators

Lead sponsor

Schön Klinik Berchtesgadener Land

Other

Registry information

Official study title

Effects of a Three Week Treadmill Versus Cycling Endurance Training on Balance, Gait Performance and Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease - a Pilot Study

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Apr 19, 2017
Registry last updated
Feb 15, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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