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Completed

NCT Number: NCT07478692

Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery

ltrasound-guided transversus abdominis plane (TAP) block is an emerging local anesthesia technique that effectively alleviates postoperative pain by injecting anesthetic drugs around the nerves in the abdominal wall. Compared with traditional analgesic methods, TAP blockade may have better analgesic effects and fewer side effects. However, current research on the application of TAP blockade after cesarean section is still limited. Therefore, this study will systematically evaluate its actual effectiveness in pain management after cesarean section through a prospective randomized controlled trial

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Key information

Conditions

Postoperative Pain After Cesarean Section

Age range

20 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Shandong Provincial Maternal and Child Health Care Hospital, Jinan, Shandong, China

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 20-40 years, in good general health
  • ASA physical status I-II
  • Singleton, term (37-41 weeks) pregnancy with normal fetal development
  • Planned for elective cesarean section, no labor

Exclusion criteria

  • Pregnancy complications (e.g., severe preeclampsia, gestational diabetes, placental abruption)
  • Major organ dysfunction (heart, liver, kidney) or psychiatric history
  • Allergy to local anesthetics or any study drugs
  • Prior abdominal surgery or infection that may affect block efficacy
  • Coagulation disorders or current anticoagulant use
  • Refusal to participate or inability to comply with follow-up

Treatment and study plan

The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg)

Drug

the control group received only the same formula intravenous analgesia pump

Primary outcomes

  1. VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity ( Time to first rescue analgesia requirement and number of patients and total dosage of flurbiprofen axetil used within 48 hours postoperatively;

    Time frame: 5 months

    VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity (coughing or turning) at 2, 6, 12, 24, and 48 hours postoperatively were recorded by anesthesiologists not involved in this study.

Sponsors and collaborators

Lead sponsor

Qing Yuan

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 17, 2026
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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