Effects of Transcranial Magnetic Stimulation After Endovascular Treatment for Acute Ischemic Stroke

Inclusion criteria

• Patients with acute anterior circulation ischemic stroke aged between 18 and 80 years old.
• Imaging suggests that the infarction is caused by occlusion of the terminal portion of the internal carotid artery or the M1/M2 segment of the middle cerebral artery.
• A head CT within 24 hours of onset indicates an ASPECT score ≥6, and meets the guideline-recommended criteria for thrombectomy.
• Pre-stroke mRS score is ≤1.
• NIHSS score before thrombectomy is between 6 and 25.
• With vascular recanalization of mTICI > 2b/3.
• Informed consent form signed.

Exclusion criteria

• Patients with contraindications to TMS treatment, such as those with metallic foreign objects in the head, pacemakers, implantable drug pumps, cochlear implants, etc.;
• Patients with epilepsy, increased intracranial pressure, tumors, acute cerebral hemorrhage, or other severe neurological diseases, and those with severe functional impairment of organs such as the heart, liver, and kidneys;
• Head CT/MRI indicates midline shift or significant mass effect, or patients planned for surgical intervention;
• Head CT/MRI suggests acute cerebral infarction in both sides;
• Patients who are pregnant or breastfeeding;
• Patients with severe mental disorders or dementia who cannot cooperate with follow-up;
• Patients with other severe diseases resulting in an expected survival of less than 90 days;
• Patients who are participating in other interventional clinical studies within 30 days before the start of this study or after the onset of this condition;
• Patients who cannot cooperate with informed consent.