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Completed

NCT Number: NCT01008020

Effects of Tea Catechin Consumption on the Prophylaxis of Influenza Infection

The Purpose of this study is to evaluate the effects of 5 months catechin consumption on the prevention of influenza infection.

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Key information

Conditions

Influenza Infection

Age range

20 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

White Cross Nursing Home

Higashimurayama, Tokyo, 189-0021, Japan

About this study

Catechins are the major components of tea flavonoids and are reported to possess physiological activities such as antiviral effects. Recent experimental studies have revealed that tea catechin extracts prevent influenza infection, but few studies have been conducted on the clinical effects of tea catechin consumption on the prophylaxis of influenza infection. Based on these backgrounds, we designed a prospective randomized controlled study to evaluate the effects of 5 months tea catechin consumption on the prophylaxis of influenza infection.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged over 20 years
  • possible to maintain without drinking tea more than 250 ml per day during the study
  • possible to maintain without taking supplements or herbal products including catechin extracts during the study
  • possible to fill out a questionnaire personally
  • Obtained written informed consent before participation

Exclusion criteria

  • Possessing some chronic infectious diseases in need of therapy
  • Possessing tea or catechin allergy
  • Possessing a history of influenza infection before six months prior to the study
  • diagnosed as inadequate for other reasons to participate the study by principal investigator

Treatment and study plan

tea catechin extracts

Dietary Supplement

Tea catechin extracts 540 mg/day, are consumed for 5 months.

Primary outcomes

  1. the incidence rates of influenza infection

    Time frame: Until 5 months consumption of the study capsules

Secondary outcomes

  1. the incidence rates of upper respiratory tract infections

    Time frame: Until 5 months consumption of the study capsules

  2. the severity of the symptoms and the duration of the cold among incident cases

    Time frame: Until 5 months consumption of the study capsules

  3. occurrence of the adverse events

    Time frame: Until 5 months consumption of the study capsules

Sponsors and collaborators

Lead sponsor

Masahiro Morikawa

Other

Collaborators

  • White Cross Nursing Home

Registry information

Official study title

A Randomized Controlled Study on the Effects of Tea Catechin Consumption on the Prevention of Influenza Infection in Healthy Adults

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Nov 5, 2009
Registry last updated
Jul 16, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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